C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: hypoxanthine phosphoribosyltransferase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000165704 HPRT1 9606 + X:134460153-134520513 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000298556 HPRT1-001 134460153-134500668 protein_coding
  ENST00000462974 HPRT1-002 134460351-134498641 processed_transcript
  ENST00000475720 HPRT1-003 134473374-134520513 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000298556ENST00000475720
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000298556 8.058±0.00 11.006±0.00 1.706±0.00 22.405±14.36 3.158±1.69 4.315±1.86 3.249±2.67 13.108±9.69 3.053±1.44 5.919±5.27 6.345±0.00 10.515±2.75 5.776±1.29 27.272±9.82
ENST00000475720 N/A N/A 2.532±0.00 9.270±0.00 2.564±0.00 4.276±0.00 1.637±0.00 3.308±0.00 1.418±0.00 1.194±0.00 1.851±0.00 28.649±0.00 17.304±0.00 78.268±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000GG CIL_0000GG_0002 CGP X:134373253-134520513
CIL_0000JX CIL_0000JX_0001 CGP X:134460153-134764322

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0000287 IDA magnesium ion binding
GO:0001975 IEA response to amphetamine
GO:0004422 IDA:IEA hypoxanthine phosphoribosyltransferase activity
GO:0005515 IPI protein binding
GO:0005737 IDA:IEA cytoplasm
GO:0005829 IBA cytosol
GO:0006144 TAS purine nucleobase metabolic process
GO:0006164 IMP purine nucleotide biosynthetic process
GO:0006166 IMP:IEA purine ribonucleoside salvage
GO:0006168 IBA adenine salvage
GO:0006178 IDA guanine salvage
GO:0007625 IEA grooming behavior
GO:0007626 IEA locomotory behavior
GO:0009116 IEA nucleoside metabolic process
GO:0019835 IEA cytolysis
GO:0021756 IEA striatum development
GO:0021895 IEA cerebral cortex neuron differentiation
GO:0021954 IEA central nervous system neuron development
GO:0032263 IBA GMP salvage
GO:0032264 IBA IMP salvage
GO:0042417 IEA dopamine metabolic process
GO:0042802 IEA identical protein binding
GO:0042803 IPI protein homodimerization activity
GO:0043101 TAS purine-containing compound salvage
GO:0043103 IDA hypoxanthine salvage
GO:0044281 TAS small molecule metabolic process
GO:0045964 IMP positive regulation of dopamine metabolic process
GO:0046038 IDA GMP catabolic process
GO:0046040 IDA IMP metabolic process
GO:0046083 IEA adenine metabolic process
GO:0046100 IMP hypoxanthine metabolic process
GO:0046651 IEA lymphocyte proliferation
GO:0048813 IEA dendrite morphogenesis
GO:0051289 IPI protein homotetramerization
GO:0052657 IDA guanine phosphoribosyltransferase activity
GO:0055086 TAS nucleobase-containing small molecule metabolic process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008884 hprt1 hypoxanthine phosphoribosyltransferase 1 protein_coding Danio_rerio
ENSMUSG00000025630 Hprt hypoxanthine guanine phosphoribosyl transferase protein_coding Mus_musculus

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