C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: hypoxanthine guanine phosphoribosyl transferase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025630 Hprt 10090 + X:52988137-53021659 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000026723 Hprt-001 52988137-53021659 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000026723
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000026723 20.592±4.10 19.685±3.06 52.627±6.56 42.604±37.34 11.925±3.04 11.392±1.48 13.160±3.12 17.924±2.92 41.435±24.67 13.575±4.11 11.883±0.35 16.252±16.96 71.570±31.16 4.232±0.68

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000GG CIL_0000GG_0003 CGP X:52912266-53021659
CIL_0000JX CIL_0000JX_0002 CGP X:52988137-53240111

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0000287 IBA magnesium ion binding
GO:0001975 IMP response to amphetamine
GO:0004422 IMP hypoxanthine phosphoribosyltransferase activity
GO:0005515 IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005829 IBA cytosol
GO:0006164 IEA purine nucleotide biosynthetic process
GO:0006166 IMP purine ribonucleoside salvage
GO:0006168 IMP adenine salvage
GO:0006178 IMP guanine salvage
GO:0007625 IGI grooming behavior
GO:0007626 IMP locomotory behavior
GO:0019835 IMP cytolysis
GO:0021756 IMP striatum development
GO:0021895 IMP cerebral cortex neuron differentiation
GO:0021954 IMP central nervous system neuron development
GO:0032263 IBA GMP salvage
GO:0032264 IBA IMP salvage
GO:0042417 IMP dopamine metabolic process
GO:0042802 IPI identical protein binding
GO:0042803 IEA protein homodimerization activity
GO:0043103 ISS hypoxanthine salvage
GO:0045964 IMP positive regulation of dopamine metabolic process
GO:0046038 ISS GMP catabolic process
GO:0046040 ISS IMP metabolic process
GO:0046083 IGI adenine metabolic process
GO:0046100 IMP hypoxanthine metabolic process
GO:0046651 IMP lymphocyte proliferation
GO:0048813 IMP dendrite morphogenesis
GO:0051289 IEA protein homotetramerization
GO:0052657 ISS guanine phosphoribosyltransferase activity
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000008884 hprt1 hypoxanthine phosphoribosyltransferase 1 protein_coding Danio_rerio
ENSG00000165704 HPRT1 hypoxanthine phosphoribosyltransferase 1 protein_coding Homo_sapiens

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