C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: gamma-aminobutyric acid (GABA) A receptor, beta 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000166206 GABRB3 9606 - 15:26543546-26939539 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000299267 GABRB3-001 26546172-26773788 protein_coding
  ENST00000311550 GABRB3-002 26543546-26773074 protein_coding
  ENST00000400188 GABRB3-006 26547189-26629090 protein_coding
  ENST00000541819 GABRB3-003 26543552-26939539 protein_coding
  ENST00000545868 GABRB3-004 26547633-26716765 protein_coding
  ENST00000554556 GABRB3-009 26561069-26773057 nonsense_mediated_decay
  ENST00000554722 GABRB3-008 26771819-26773751 processed_transcript
  ENST00000555094 GABRB3-011 26580331-26767236 protein_coding
  ENST00000555632 GABRB3-012 26547256-26773014 nonsense_mediated_decay
  ENST00000556166 GABRB3-005 26615297-26629178 nonsense_mediated_decay
  ENST00000556636 GABRB3-013 26615297-26621406 nonsense_mediated_decay
  ENST00000557641 GABRB3-010 26749935-26790300 processed_transcript
  ENST00000557765 GABRB3-014 26561123-26580671 retained_intron
  ENST00000621499 GABRB3-007 26611858-26615717 processed_transcript
  ENST00000622697 GABRB3-201 26543549-26773076 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyMuscleOvaryPlacentaTestisENST00000299267ENST00000311550ENST00000400188ENST00000545868ENST00000555094ENST00000621499
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Muscle Ovary Placenta Testis
ENST00000299267 N/A N/A 0.882±0.00 5.988±0.00 0.160±0.00 N/A N/A 0.141±0.00 N/A 0.029±0.02 0.035±0.01 0.588±0.00
ENST00000311550 N/A N/A N/A 12.650±0.72 0.033±0.02 0.243±0.06 N/A N/A 0.010±0.00 0.395±0.00 0.041±0.00 N/A
ENST00000400188 0.067±0.00 N/A N/A N/A N/A N/A 0.181±0.04 N/A 0.090±0.06 N/A N/A N/A
ENST00000545868 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.028±0.02 N/A
ENST00000555094 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.153±0.00
ENST00000621499 0.016±0.00 0.176±0.00 N/A N/A 0.057±0.00 N/A 0.091±0.00 N/A 0.044±0.00 0.062±0.00 N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004890 IEA:IMP GABA-A receptor activity
GO:0005230 IEA extracellular ligand-gated ion channel activity
GO:0005254 IEA chloride channel activity
GO:0005886 TAS plasma membrane
GO:0005887 IMP integral component of plasma membrane
GO:0006810 TAS:IEA transport
GO:0006811 IEA ion transport
GO:0007165 IEA:TAS signal transduction
GO:0007268 TAS synaptic transmission
GO:0007605 IEA sensory perception of sound
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0022851 ISS GABA-gated chloride ion channel activity
GO:0030054 IEA cell junction
GO:0034220 IEA:TAS ion transmembrane transport
GO:0034707 IEA chloride channel complex
GO:0043523 IEA regulation of neuron apoptotic process
GO:0043524 IEA negative regulation of neuron apoptotic process
GO:0045202 IEA synapse
GO:0045211 IEA postsynaptic membrane
GO:0048666 IEA neuron development
GO:0055085 TAS transmembrane transport
GO:0060021 ISS palate development
GO:0060119 IEA inner ear receptor cell development
GO:0060384 IEA innervation
GO:0071420 IDA cellular response to histamine
GO:0090102 IEA cochlea development
GO:1901215 IEA negative regulation of neuron death
GO:1902476 ISS chloride transmembrane transport
GO:1902711 ISS GABA-A receptor complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000023771 gabrb3 gamma-aminobutyric acid (GABA) A receptor, beta 3 protein_coding Danio_rerio
ENSMUSG00000033676 Gabrb3 gamma-aminobutyric acid (GABA) A receptor, subunit beta 3 protein_coding Mus_musculus

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