C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: pleckstrin homology domain containing, family F (with FYVE domain) member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000166289 PLEKHF1 9606 + 19:29665056-29675457 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000436066 PLEKHF1-001 29665056-29675457 protein_coding
  ENST00000586888 PLEKHF1-004 29666874-29674223 protein_coding
  ENST00000588833 PLEKHF1-003 29665501-29674085 protein_coding
  ENST00000592810 PLEKHF1-002 29665459-29674843 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000436066ENST00000586888ENST00000592810
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000436066 3.244±0.00 8.516±0.00 1.395±1.30 6.310±5.42 1.760±1.44 2.778±2.04 3.430±0.00 5.328±0.00 2.715±2.06 20.526±11.65 15.260±9.99 9.685±2.92 4.576±3.01
ENST00000586888 N/A N/A 0.540±0.00 0.569±0.00 0.788±0.00 N/A N/A 1.228±0.00 N/A 9.066±0.00 12.508±0.00 N/A N/A
ENST00000592810 1.966±0.00 3.194±0.00 1.586±0.00 N/A 2.599±0.00 1.710±1.29 1.043±0.00 N/A 2.301±0.00 N/A 3.639±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008TZ CIL_0008TZ_0001 VISTA 19:29588658-30189738

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005634 IEA nucleus
GO:0005764 IDA lysosome
GO:0005765 IC lysosomal membrane
GO:0005768 IDA endosome
GO:0006915 IEA apoptotic process
GO:0007032 IMP endosome organization
GO:0010008 IC endosome membrane
GO:0010314 IDA phosphatidylinositol-5-phosphate binding
GO:0010508 IDA positive regulation of autophagy
GO:0016050 IMP vesicle organization
GO:0032266 IDA phosphatidylinositol-3-phosphate binding
GO:0046872 IEA metal ion binding
GO:0070273 IDA phosphatidylinositol-4-phosphate binding
GO:0072659 IMP protein localization to plasma membrane
GO:2001244 IEA positive regulation of intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000074170 Plekhf1 pleckstrin homology domain containing, family F (with FYVE domain) member 1 protein_coding Mus_musculus

Loading