C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serpin peptidase inhibitor, clade B (ovalbumin), member 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000166401 SERPINB8 9606 + 18:63969925-64005667 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000295211 SERPINB8-003 63979808-63987396 protein_coding
  ENST00000353706 SERPINB8-201 63970029-63989371 protein_coding
  ENST00000397985 SERPINB8-001 63969925-63989374 protein_coding
  ENST00000397988 SERPINB8-002 63970119-63986653 protein_coding
  ENST00000441827 SERPINB8-006 63970505-63983647 protein_coding
  ENST00000448851 SERPINB8-005 63970249-63981786 protein_coding
  ENST00000493661 SERPINB8-004 63985176-64005667 protein_coding
  ENST00000542677 SERPINB8-202 63970029-63989371 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000295211ENST00000353706ENST00000397985ENST00000397988ENST00000441827ENST00000542677
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000295211 2.348±0.00 3.422±0.00 2.027±0.00 1.338±0.00 1.358±0.00 N/A 1.893±0.18 4.031±0.00 2.082±0.04 1.799±0.00 0.951±0.16 1.633±0.47 1.626±0.00
ENST00000353706 N/A N/A N/A 0.731±0.00 N/A N/A N/A 1.909±0.00 2.025±0.00 N/A N/A 0.406±0.00 N/A
ENST00000397985 0.585±0.00 N/A 0.141±0.00 1.613±0.00 0.368±0.00 0.193±0.00 0.765±0.00 0.663±0.00 0.824±0.00 N/A 0.370±0.16 0.471±0.11 N/A
ENST00000397988 N/A N/A N/A N/A N/A 0.070±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000441827 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.676±0.00
ENST00000542677 N/A N/A N/A N/A 0.231±0.00 0.333±0.00 0.469±0.00 0.167±0.00 0.504±0.00 0.400±0.12 0.283±0.00 0.374±0.00 0.350±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00076K CIL_00076K_0001 CGP 18:63969925-65890341

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004867 IDA serine-type endopeptidase inhibitor activity
GO:0005515 IPI protein binding
GO:0005615 IEA extracellular space
GO:0005829 IDA cytosol
GO:0010951 IDA negative regulation of endopeptidase activity
GO:0030162 IBA regulation of proteolysis
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014556 serpinb1l3 serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 3 protein_coding Danio_rerio
ENSDARG00000057263 zgc:173729 zgc:173729 protein_coding Danio_rerio
ENSDARG00000091801 si:ch73-303g23.4 si:ch73-303g23.4 protein_coding Danio_rerio
ENSDARG00000095830 serpinb1l1 serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 1 protein_coding Danio_rerio
ENSDARG00000096888 serpinb1l4 serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 4 protein_coding Danio_rerio
ENSMUSG00000026315 Serpinb8 serine (or cysteine) peptidase inhibitor, clade B, member 8 protein_coding Mus_musculus

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