C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serine (or cysteine) peptidase inhibitor, clade B, member 8
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026315 Serpinb8 10090 + 1:107590006-107610484 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000000514 Serpinb8-002 107590006-107608909 protein_coding
  ENSMUST00000112706 Serpinb8-001 107590006-107610484 protein_coding
  ENSMUST00000123086 Serpinb8-004 107605880-107607325 protein_coding
  ENSMUST00000151283 Serpinb8-003 107590046-107606150 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000000514ENSMUST00000112706ENSMUST00000123086ENSMUST00000151283
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000000514 1.893±0.10 0.510±0.11 2.706±0.12 0.043±0.03 1.599±0.70 0.513±0.10 0.606±0.17 5.324±1.14 0.970±0.95 2.226±0.61 0.151±0.08 1.587±0.80 0.193±0.13 0.044±0.01
ENSMUST00000112706 0.833±0.16 0.441±0.18 1.268±0.37 0.065±0.00 0.952±0.44 0.215±0.07 0.253±0.08 1.659±0.00 0.188±0.18 1.415±0.43 0.051±0.00 0.513±0.30 0.069±0.05 0.046±0.02
ENSMUST00000123086 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.257±0.00 0.155±0.00
ENSMUST00000151283 N/A N/A N/A 0.056±0.00 N/A 0.291±0.04 N/A N/A N/A N/A 0.146±0.03 0.943±0.03 0.117±0.04 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000160 CIL_000160_000Y CGP 1:107529003-107610484
CIL_00076K CIL_00076K_0002 CGP 1:107590006-110140157

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004867 IBA serine-type endopeptidase inhibitor activity
GO:0005515 IEA protein binding
GO:0005615 IEA extracellular space
GO:0005737 IBA cytoplasm
GO:0005829 IEA cytosol
GO:0010951 IBA negative regulation of endopeptidase activity
GO:0030162 IBA regulation of proteolysis
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014556 serpinb1l3 serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 3 protein_coding Danio_rerio
ENSDARG00000057263 zgc:173729 zgc:173729 protein_coding Danio_rerio
ENSDARG00000091801 si:ch73-303g23.4 si:ch73-303g23.4 protein_coding Danio_rerio
ENSDARG00000095830 serpinb1l1 serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 1 protein_coding Danio_rerio
ENSDARG00000096888 serpinb1l4 serpin peptidase inhibitor, clade B (ovalbumin), member 1, like 4 protein_coding Danio_rerio
ENSG00000166401 SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 protein_coding Homo_sapiens

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