C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: heat shock protein 90kDa beta (Grp94), member 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000166598 HSP90B1 9606 + 12:103930107-103953645 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000299767 HSP90B1-001 103930334-103947926 protein_coding
  ENST00000540297 HSP90B1-008 103930410-103933990 nonsense_mediated_decay
  ENST00000548462 HSP90B1-003 103930438-103947927 retained_intron
  ENST00000548622 HSP90B1-007 103930382-103932176 retained_intron
  ENST00000549334 HSP90B1-006 103930107-103932929 protein_coding
  ENST00000550479 HSP90B1-009 103938238-103941768 retained_intron
  ENST00000550595 HSP90B1-012 103943796-103953645 protein_coding
  ENST00000551983 HSP90B1-010 103941834-103943467 retained_intron
  ENST00000552051 HSP90B1-011 103943619-103947400 retained_intron
  ENST00000614327 HSP90B1-201 103930438-103947901 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000299767ENST00000550595ENST00000552051ENST00000614327
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000299767 101.231±0.00 235.799±0.00 27.746±0.00 47.462±23.97 101.720±8.43 140.349±102.97 41.646±27.21 160.085±54.41 197.688±162.48 126.130±70.19 15.099±11.41 167.733±61.81 298.515±83.16 141.003±1.25
ENST00000550595 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 205.678±0.00 86.694±0.00
ENST00000552051 N/A N/A N/A 37.094±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 589.618±0.00 339.420±0.00
ENST00000614327 N/A N/A 22.209±0.00 N/A N/A N/A N/A N/A 15.773±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001666 IDA response to hypoxia
GO:0002224 TAS toll-like receptor signaling pathway
GO:0003723 IDA RNA binding
GO:0005509 TAS calcium ion binding
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005576 TAS extracellular region
GO:0005634 IDA nucleus
GO:0005783 IDA endoplasmic reticulum
GO:0005788 IDA endoplasmic reticulum lumen
GO:0005789 IDA endoplasmic reticulum membrane
GO:0005829 IDA cytosol
GO:0005886 IEA plasma membrane
GO:0005925 IDA focal adhesion
GO:0006457 IEA protein folding
GO:0006950 IEA response to stress
GO:0006987 TAS activation of signaling protein activity involved in unfolded protein response
GO:0015031 NAS protein transport
GO:0016020 IDA membrane
GO:0019903 IDA protein phosphatase binding
GO:0030433 IMP ER-associated ubiquitin-dependent protein catabolic process
GO:0030496 IDA midbody
GO:0030968 TAS endoplasmic reticulum unfolded protein response
GO:0031012 IDA extracellular matrix
GO:0031247 IDA actin rod assembly
GO:0043066 IMP negative regulation of apoptotic process
GO:0043666 IDA regulation of phosphoprotein phosphatase activity
GO:0044267 TAS cellular protein metabolic process
GO:0045087 TAS innate immune response
GO:0046790 IPI virion binding
GO:0048471 IDA perinuclear region of cytoplasm
GO:0050750 IDA low-density lipoprotein particle receptor binding
GO:0051082 IEA unfolded protein binding
GO:0051208 NAS sequestering of calcium ion
GO:0070062 IDA extracellular vesicular exosome
GO:0071318 IDA cellular response to ATP
GO:0071682 TAS endocytic vesicle lumen

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003570 hsp90b1 heat shock protein 90, beta (grp94), member 1 protein_coding Danio_rerio
ENSMUSG00000020048 Hsp90b1 heat shock protein 90, beta (Grp94), member 1 protein_coding Mus_musculus

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