C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: methionyl-tRNA synthetase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000166986 MARS 9606 + 12:57475445-57517569 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000262027 MARS-003 57487957-57516649 protein_coding
  ENST00000447721 MARS-005 57488068-57512154 processed_transcript
  ENST00000537638 MARS-002 57487294-57517569 nonsense_mediated_decay
  ENST00000545888 MARS-004 57488066-57516655 nonsense_mediated_decay
  ENST00000546481 MARS-007 57488062-57489519 retained_intron
  ENST00000546971 MARS-024 57511586-57512964 retained_intron
  ENST00000547062 MARS-010 57488068-57489457 retained_intron
  ENST00000547501 MARS-013 57488068-57490234 nonsense_mediated_decay
  ENST00000547665 MARS-033 57515150-57516655 protein_coding
  ENST00000548146 MARS-016 57488212-57489283 processed_transcript
  ENST00000548202 MARS-027 57512491-57515234 retained_intron
  ENST00000548630 MARS-025 57511769-57512464 retained_intron
  ENST00000548674 MARS-008 57488024-57498241 processed_transcript
  ENST00000548714 MARS-011 57488068-57489610 retained_intron
  ENST00000548944 MARS-034 57500358-57516655 protein_coding
  ENST00000549048 MARS-026 57511797-57514842 retained_intron
  ENST00000549074 MARS-015 57488068-57498185 nonsense_mediated_decay
  ENST00000549133 MARS-001 57475445-57487473 processed_transcript
  ENST00000549603 MARS-022 57503986-57511785 retained_intron
  ENST00000549827 MARS-023 57500114-57504280 retained_intron
  ENST00000550449 MARS-009 57488056-57490342 retained_intron
  ENST00000551172 MARS-031 57515183-57516647 nonsense_mediated_decay
  ENST00000551431 MARS-014 57488068-57490621 nonsense_mediated_decay
  ENST00000551805 MARS-028 57514822-57515493 retained_intron
  ENST00000551842 MARS-012 57488068-57489783 retained_intron
  ENST00000551892 MARS-018 57488085-57500423 nonsense_mediated_decay
  ENST00000552007 MARS-019 57488085-57490358 nonsense_mediated_decay
  ENST00000552371 MARS-021 57489530-57500430 protein_coding
  ENST00000552499 MARS-029 57515181-57516648 nonsense_mediated_decay
  ENST00000552914 MARS-030 57512930-57516655 protein_coding
  ENST00000553123 MARS-017 57488686-57490216 retained_intron
  ENST00000553162 MARS-020 57488068-57490033 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000262027ENST00000447721ENST00000545888ENST00000551892ENST00000552914ENST00000553162
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000262027 18.255±0.00 27.355±0.00 N/A 14.877±5.48 10.299±3.72 7.109±3.80 8.850±7.21 15.259±11.49 9.352±5.17 11.305±8.45 24.146±19.13 24.145±11.54 27.526±5.15 38.534±4.17
ENST00000447721 N/A N/A 4.588±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000545888 N/A 22.511±0.00 3.560±0.00 4.403±0.00 4.081±0.00 2.988±0.00 N/A N/A N/A 7.652±2.37 N/A 7.970±3.85 N/A N/A
ENST00000551892 N/A N/A N/A N/A N/A 13.178±0.00 3.888±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000552914 N/A N/A N/A N/A N/A N/A N/A 4.766±0.00 24.729±0.00 N/A 12.481±0.00 65.218±0.00 28.405±0.00 49.688±0.00
ENST00000553162 N/A N/A N/A N/A N/A N/A N/A N/A 15.927±0.00 18.535±0.00 N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000049 IEA tRNA binding
GO:0000166 IEA nucleotide binding
GO:0004812 IEA aminoacyl-tRNA ligase activity
GO:0004825 TAS:IEA methionine-tRNA ligase activity
GO:0005524 IEA ATP binding
GO:0005737 IDA:IEA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005829 TAS cytosol
GO:0006418 TAS:IEA tRNA aminoacylation for protein translation
GO:0006431 IEA methionyl-tRNA aminoacylation
GO:0010467 TAS gene expression
GO:0016020 IDA membrane
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000034396 mars methionine-tRNA synthetase protein_coding Danio_rerio
ENSMUSG00000040354 Mars methionine-tRNA synthetase protein_coding Mus_musculus

Loading