C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: v-crk avian sarcoma virus CT10 oncogene homolog
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000167193 CRK 9606 - 17:1420689-1463162 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000300574 CRK-001 1420689-1456258 protein_coding
  ENST00000398970 CRK-002 1420689-1456223 protein_coding
  ENST00000572145 CRK-004 1423397-1463162 processed_transcript
  ENST00000574295 CRK-003 1422226-1456149 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000300574ENST00000398970ENST00000572145ENST00000574295
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000300574 17.149±0.00 7.368±0.00 1.311±0.00 4.220±0.88 10.450±9.51 10.078±5.63 5.692±2.87 7.082±1.74 5.006±0.22 10.408±8.74 4.980±2.03 7.240±1.94 11.915±4.74 12.877±2.66
ENST00000398970 14.784±0.00 10.228±0.00 3.234±0.00 5.650±3.48 5.945±3.32 9.175±0.00 2.277±1.55 9.059±0.00 6.004±2.08 5.233±0.00 3.639±0.00 5.538±3.59 7.384±2.79 6.254±0.00
ENST00000572145 N/A N/A 2.490±0.00 6.391±0.00 4.477±0.00 8.922±0.00 3.106±0.00 13.142±0.00 8.108±0.00 7.347±0.00 6.372±0.00 8.795±1.19 19.833±0.00 16.529±0.00
ENST00000574295 N/A N/A N/A N/A N/A N/A N/A 4.783±0.00 N/A N/A N/A 8.182±0.00 15.433±0.00 10.577±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000186 TAS activation of MAPKK activity
GO:0005070 IEA SH3/SH2 adaptor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 TAS nucleus
GO:0005737 IC cytoplasm
GO:0005829 TAS cytosol
GO:0005886 IEA plasma membrane
GO:0006357 TAS regulation of transcription from RNA polymerase II promoter
GO:0007596 TAS blood coagulation
GO:0008286 TAS insulin receptor signaling pathway
GO:0009967 IEA positive regulation of signal transduction
GO:0015629 IEA actin cytoskeleton
GO:0019904 IEA protein domain specific binding
GO:0030168 TAS platelet activation
GO:0030674 IEA protein binding, bridging
GO:0032319 IDA regulation of Rho GTPase activity
GO:0032956 IDA regulation of actin cytoskeleton organization
GO:0035020 IEA regulation of Rac protein signal transduction
GO:0038096 TAS Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0042169 IPI SH2 domain binding
GO:0045087 TAS innate immune response
GO:0045309 IEA protein phosphorylated amino acid binding
GO:0046875 IPI ephrin receptor binding
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048013 IDA ephrin receptor signaling pathway
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055635 crk v-crk sarcoma virus CT10 oncogene homolog (avian) protein_coding Danio_rerio
ENSMUSG00000017776 Crk v-crk sarcoma virus CT10 oncogene homolog (avian) protein_coding Mus_musculus

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