C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: v-crk avian sarcoma virus CT10 oncogene homolog
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000300574 CRK-001 ENSG00000167193 9606 - 17:1420689-1456258 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000300574
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000300574 17.149±0.00 7.368±0.00 1.311±0.00 4.220±0.88 10.450±9.51 10.078±5.63 5.692±2.87 7.082±1.74 5.006±0.22 10.408±8.74 4.980±2.03 7.240±1.94 11.915±4.74 12.877±2.66

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000186 TAS activation of MAPKK activity
GO:0005070 IEA SH3/SH2 adaptor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 TAS nucleus
GO:0005737 IC cytoplasm
GO:0005829 TAS cytosol
GO:0005886 IEA plasma membrane
GO:0006357 TAS regulation of transcription from RNA polymerase II promoter
GO:0007596 TAS blood coagulation
GO:0008286 TAS insulin receptor signaling pathway
GO:0009967 IEA positive regulation of signal transduction
GO:0015629 IEA actin cytoskeleton
GO:0019904 IEA protein domain specific binding
GO:0030168 TAS platelet activation
GO:0030674 IEA protein binding, bridging
GO:0032319 IDA regulation of Rho GTPase activity
GO:0032956 IDA regulation of actin cytoskeleton organization
GO:0035020 IEA regulation of Rac protein signal transduction
GO:0038096 TAS Fc-gamma receptor signaling pathway involved in phagocytosis
GO:0042169 IPI SH2 domain binding
GO:0045087 TAS innate immune response
GO:0045309 IEA protein phosphorylated amino acid binding
GO:0046875 IPI ephrin receptor binding
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0048013 IDA ephrin receptor signaling pathway
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000017920 Crk-001 protein_coding Mus_musculus 0 2326
ENSMUST00000108425 Crk-002 protein_coding Mus_musculus 0 1112
ENSMUST00000093115 Crk-003 protein_coding Mus_musculus 0 1070
ENSMUST00000147718 Crk-005 protein_coding Mus_musculus 0 1062
ENSMUST00000108426 Crk-004 protein_coding Mus_musculus 0 538

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