C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: v-crk sarcoma virus CT10 oncogene homolog (avian)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000017776 Crk 10090 + 11:75679259-75706908 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000017920 Crk-001 75679259-75706065 protein_coding
  ENSMUST00000093115 Crk-003 75679311-75700789 protein_coding
  ENSMUST00000108425 Crk-002 75679284-75706908 protein_coding
  ENSMUST00000108426 Crk-004 75679284-75703655 protein_coding
  ENSMUST00000147718 Crk-005 75679542-75700737 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000017920ENSMUST00000093115ENSMUST00000108425ENSMUST00000108426ENSMUST00000147718
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000017920 23.955±2.89 17.889±2.82 30.865±7.46 23.335±8.31 20.010±3.54 20.525±4.78 18.747±2.23 23.316±1.50 14.955±2.98 27.778±2.85 8.304±4.45 22.663±5.30 34.065±10.36 3.279±2.17
ENSMUST00000093115 N/A 26.147±5.40 N/A N/A N/A 16.617±0.00 N/A N/A N/A N/A N/A N/A N/A 11.981±2.85
ENSMUST00000108425 3.804±1.56 N/A 4.498±0.00 4.443±1.33 3.348±0.98 5.001±0.24 2.177±0.00 4.809±0.55 3.438±0.80 5.585±0.54 N/A 3.730±0.84 5.435±0.00 N/A
ENSMUST00000108426 N/A 64.497±27.16 N/A N/A 29.335±0.66 48.866±18.38 N/A 19.653±0.00 9.714±2.23 N/A N/A 33.319±20.61 N/A N/A
ENSMUST00000147718 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 26.851±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000034 CIL_000034_0002 CGP 11:75679259-75765845

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005070 IPI SH3/SH2 adaptor activity
GO:0005515 IPI protein binding
GO:0005737 IEA cytoplasm
GO:0005886 IEA plasma membrane
GO:0009967 IPI positive regulation of signal transduction
GO:0015629 IDA actin cytoskeleton
GO:0019904 IEA protein domain specific binding
GO:0030674 IEA protein binding, bridging
GO:0032319 ISS regulation of Rho GTPase activity
GO:0032956 ISS regulation of actin cytoskeleton organization
GO:0035020 IEA regulation of Rac protein signal transduction
GO:0042169 IEA SH2 domain binding
GO:0045309 IDA protein phosphorylated amino acid binding
GO:0046875 IPI ephrin receptor binding
GO:0048013 ISS ephrin receptor signaling pathway
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055635 crk v-crk sarcoma virus CT10 oncogene homolog (avian) protein_coding Danio_rerio
ENSG00000167193 CRK v-crk avian sarcoma virus CT10 oncogene homolog protein_coding Homo_sapiens

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