C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: vitamin K epoxide reductase complex, subunit 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000167397 VKORC1 9606 - 16:31090842-31095980 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000300851 VKORC1-004 31090842-31094760 protein_coding
  ENST00000319788 VKORC1-002 31090842-31094940 protein_coding
  ENST00000354895 VKORC1-003 31090842-31094956 protein_coding
  ENST00000394971 VKORC1-006 31091104-31094549 protein_coding
  ENST00000394975 VKORC1-001 31090842-31094957 protein_coding
  ENST00000420057 VKORC1-008 31090842-31095633 protein_coding
  ENST00000472468 VKORC1-005 31091182-31093611 protein_coding
  ENST00000498155 VKORC1-007 31091175-31095980 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000300851ENST00000354895ENST00000394975
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000300851 19.677±0.00 37.586±0.00 5.456±0.00 3.826±0.00 22.826±15.83 30.409±0.00 6.505±4.99 22.532±0.15 57.320±0.00 25.768±20.01 3.161±1.69 5.259±0.00 N/A N/A
ENST00000354895 N/A N/A N/A N/A N/A 7.510±0.00 N/A 8.170±0.00 N/A N/A 3.522±0.00 N/A N/A N/A
ENST00000394975 29.758±0.00 28.288±0.00 N/A 26.621±0.00 37.216±0.00 39.002±0.00 9.384±0.00 57.686±0.00 71.085±60.99 29.886±0.00 6.667±0.00 56.843±29.65 57.323±22.14 58.369±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001VX CIL_0001VX_0001 CGP 16:31083425-31094956
CIL_0006UE CIL_0006UE_0001 CGP 16:31083439-31095980
CIL_0006UF CIL_0006UF_0001 CGP 16:31090842-31112791

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005789 TAS endoplasmic reticulum membrane
GO:0007596 IMP blood coagulation
GO:0016021 IEA integral component of membrane
GO:0017144 IMP drug metabolic process
GO:0017187 IMP peptidyl-glutamic acid carboxylation
GO:0042373 IDA vitamin K metabolic process
GO:0043687 TAS post-translational protein modification
GO:0044267 TAS cellular protein metabolic process
GO:0047057 IDA vitamin-K-epoxide reductase (warfarin-sensitive) activity
GO:0048038 IEA quinone binding
GO:0055114 IEA oxidation-reduction process
GO:0060348 ISS bone development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000086183 vkorc1 vitamin K epoxide reductase complex, subunit 1 protein_coding Danio_rerio
ENSMUSG00000030804 Gm21974 predicted gene 21974 protein_coding Mus_musculus
ENSMUSG00000096145 Vkorc1 vitamin K epoxide reductase complex, subunit 1 protein_coding Mus_musculus

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