C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: vitamin K epoxide reductase complex, subunit 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000096145 Vkorc1 10090 - 7:127893067-127895617 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000033074 Vkorc1-001 127893067-127895617 protein_coding
  ENSMUST00000119922 Vkorc1-002 127893238-127895309 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000033074ENSMUST00000119922
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000033074 127.107±6.00 119.654±26.66 106.517±8.60 35.618±3.43 135.804±25.97 86.896±7.86 26.342±3.07 127.999±16.93 252.782±114.31 99.450±17.15 11.099±1.33 143.684±62.74 81.328±54.61
ENSMUST00000119922 N/A N/A N/A N/A 106.325±0.00 N/A N/A 99.418±24.16 204.744±17.97 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001VX CIL_0001VX_0002 CGP 7:127885841-127895454
CIL_0006UE CIL_0006UE_0002 CGP 7:127886227-127895617
CIL_0006UF CIL_0006UF_0002 CGP 7:127893067-127909664

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005783 ISA endoplasmic reticulum
GO:0007596 IMP blood coagulation
GO:0016021 IEA integral component of membrane
GO:0017187 ISS peptidyl-glutamic acid carboxylation
GO:0042371 ISA vitamin K biosynthetic process
GO:0042373 IDA vitamin K metabolic process
GO:0047057 ISA vitamin-K-epoxide reductase (warfarin-sensitive) activity
GO:0048038 IEA quinone binding
GO:0050820 IMP positive regulation of coagulation
GO:0055114 ISA:IEA oxidation-reduction process
GO:0060348 IMP bone development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000086183 vkorc1 vitamin K epoxide reductase complex, subunit 1 protein_coding Danio_rerio
ENSG00000167397 VKORC1 vitamin K epoxide reductase complex, subunit 1 protein_coding Homo_sapiens
ENSG00000255439 RP11-196G11.1 Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000431371} protein_coding Homo_sapiens

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