C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nucleoredoxin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000167693 NXN 9606 - 17:799313-979770 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000336868 NXN-001 799313-979770 protein_coding
  ENST00000537628 NXN-002 800768-864097 protein_coding
  ENST00000571080 NXN-012 978299-979462 retained_intron
  ENST00000571281 NXN-007 800388-803984 retained_intron
  ENST00000571338 NXN-009 823687-930051 processed_transcript
  ENST00000571684 NXN-003 800481-826001 protein_coding
  ENST00000574018 NXN-008 800788-805248 processed_transcript
  ENST00000575171 NXN-006 825566-979349 retained_intron
  ENST00000575455 NXN-004 819114-897014 retained_intron
  ENST00000575801 NXN-005 799313-864111 protein_coding
  ENST00000576991 NXN-011 929956-933413 processed_transcript
  ENST00000577098 NXN-010 823646-908034 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000336868ENST00000537628ENST00000571684ENST00000575455ENST00000575801
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000336868 13.497±0.00 9.765±0.00 1.665±1.24 3.633±2.76 13.379±12.40 3.941±0.00 4.460±0.00 4.386±0.00 7.882±6.46 37.671±33.06 10.416±8.48 14.266±2.05 5.354±3.30
ENST00000537628 N/A N/A N/A N/A N/A N/A 1.777±0.00 N/A N/A N/A 0.684±0.00 N/A N/A
ENST00000571684 N/A N/A 1.954±0.00 3.996±0.00 0.841±0.00 1.705±0.00 N/A 4.068±0.00 N/A N/A N/A N/A N/A
ENST00000575455 N/A N/A 0.912±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000575801 N/A N/A N/A 1.882±0.61 15.311±0.00 0.804±0.00 N/A 3.190±0.00 0.812±0.00 1.778±0.00 4.839±1.45 2.185±0.16 6.400±3.36

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006AF CIL_0006AF_0002 CGP 17:782273-979770
CIL_0001Q9 CIL_0001Q9_0001 CGP 17:799313-1003671

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004791 IEA thioredoxin-disulfide reductase activity
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0016055 IEA Wnt signaling pathway
GO:0016209 IEA antioxidant activity
GO:0016491 IEA oxidoreductase activity
GO:0030154 IEA cell differentiation
GO:0030178 ISS negative regulation of Wnt signaling pathway
GO:0031397 ISS negative regulation of protein ubiquitination
GO:0045454 IEA cell redox homeostasis
GO:0047134 IEA protein-disulfide reductase activity
GO:0055114 IEA oxidation-reduction process
GO:0072358 ISS cardiovascular system development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000033978 nxn nucleoredoxin protein_coding Danio_rerio
ENSMUSG00000020844 Nxn nucleoredoxin protein_coding Mus_musculus

Loading