C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nucleoredoxin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020844 Nxn 10090 - 11:76257198-76399140 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000021204 Nxn-001 76257198-76399140 protein_coding
  ENSMUST00000131472 Nxn-002 76358803-76399068 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000021204ENSMUST00000131472
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000021204 15.025±8.62 11.421±0.25 20.568±0.38 6.114±3.23 9.831±3.27 8.850±0.58 4.678±0.14 4.745±0.18 1.319±0.79 9.224±0.09 16.828±0.74 22.434±4.44 2.838±1.15 37.288±10.75
ENSMUST00000131472 N/A 9.708±2.97 N/A N/A N/A N/A N/A N/A 0.247±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006AF CIL_0006AF_0003 CGP 11:76243715-76399140
CIL_0001Q9 CIL_0001Q9_0002 CGP 11:76257198-76416292

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004791 IDA thioredoxin-disulfide reductase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0016055 IEA Wnt signaling pathway
GO:0030154 IEA cell differentiation
GO:0030178 IMP negative regulation of Wnt signaling pathway
GO:0031397 IMP negative regulation of protein ubiquitination
GO:0047134 IEA protein-disulfide reductase activity
GO:0055114 IEA oxidation-reduction process
GO:0072358 IMP cardiovascular system development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000033978 nxn nucleoredoxin protein_coding Danio_rerio
ENSG00000167693 NXN nucleoredoxin protein_coding Homo_sapiens

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