C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: damage-specific DNA binding protein 1, 127kDa
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000167986 DDB1 9606 - 11:61299451-61342596 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000301764 DDB1-001 61299451-61333366 protein_coding
  ENST00000414411 DDB1-022 61313673-61315750 retained_intron
  ENST00000451943 DDB1-026 61299556-61302914 protein_coding
  ENST00000535147 DDB1-021 61310296-61316285 protein_coding
  ENST00000535174 DDB1-013 61316281-61326924 protein_coding
  ENST00000535283 DDB1-007 61329326-61332386 protein_coding
  ENST00000535967 DDB1-018 61313860-61322958 protein_coding
  ENST00000537120 DDB1-014 61323758-61333041 retained_intron
  ENST00000537877 DDB1-019 61313538-61322164 protein_coding
  ENST00000538129 DDB1-010 61329362-61330209 retained_intron
  ENST00000538280 DDB1-027 61314338-61316569 processed_transcript
  ENST00000538470 DDB1-025 61300071-61303357 protein_coding
  ENST00000539332 DDB1-024 61302581-61311349 protein_coding
  ENST00000539426 DDB1-009 61326779-61332835 protein_coding
  ENST00000539712 DDB1-020 61321255-61326897 retained_intron
  ENST00000539739 DDB1-017 61314047-61323886 protein_coding
  ENST00000540166 DDB1-002 61300051-61342596 nonsense_mediated_decay
  ENST00000540784 DDB1-016 61314048-61324266 retained_intron
  ENST00000541513 DDB1-015 61322317-61326229 protein_coding
  ENST00000542337 DDB1-008 61329474-61333224 protein_coding
  ENST00000543162 DDB1-011 61324084-61333066 processed_transcript
  ENST00000543627 DDB1-006 61329957-61333775 protein_coding
  ENST00000543658 DDB1-012 61309809-61333053 protein_coding
  ENST00000545894 DDB1-023 61299681-61302551 retained_intron
  ENST00000545930 DDB1-005 61314453-61327551 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000301764ENST00000451943
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000301764 41.947±0.00 20.284±0.00 15.593±0.00 43.533±16.99 23.505±7.77 19.094±0.58 18.697±7.87 26.316±12.52 20.413±0.28 21.939±6.00 41.424±22.60 43.812±41.81 78.495±11.77 36.182±10.49
ENST00000451943 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 95.025±0.00 79.856±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007WT CIL_0007WT_0001 VISTA 11:61244303-61847279

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000718 TAS nucleotide-excision repair, DNA damage removal
GO:0003676 IEA nucleic acid binding
GO:0003677 TAS DNA binding
GO:0003684 IDA damaged DNA binding
GO:0003824 IEA catalytic activity
GO:0005515 IPI protein binding
GO:0005615 IDA extracellular space
GO:0005634 IEA:IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0006281 TAS DNA repair
GO:0006289 TAS nucleotide-excision repair
GO:0016032 IEA viral process
GO:0016055 IEA Wnt signaling pathway
GO:0031464 IDA Cul4A-RING E3 ubiquitin ligase complex
GO:0031465 IDA Cul4B-RING E3 ubiquitin ligase complex
GO:0035518 IDA histone H2A monoubiquitination
GO:0042787 IDA protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0043066 IEA negative regulation of apoptotic process
GO:0043161 IMP proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070062 IDA extracellular vesicular exosome
GO:0070914 IDA UV-damage excision repair
GO:0080008 IDA Cul4-RING E3 ubiquitin ligase complex
GO:1901990 IMP regulation of mitotic cell cycle phase transition

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074431 ddb1 damage specific DNA binding protein 1 protein_coding Danio_rerio
ENSDARG00000089106 ddb1 damage specific DNA binding protein 1 protein_coding Danio_rerio
ENSMUSG00000024740 Ddb1 damage specific DNA binding protein 1 protein_coding Mus_musculus

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