C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: damage specific DNA binding protein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024740 Ddb1 10090 + 19:10605625-10629813 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000025649 Ddb1-201 10605625-10629813 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000025649
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000025649 89.925±19.93 60.797±16.15 66.831±10.34 57.050±23.68 50.033±23.02 47.855±8.49 30.588±2.86 63.785±4.58 52.952±21.64 65.277±3.75 43.237±2.62 93.492±27.21 251.921±111.52 41.939±17.68

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007WT CIL_0007WT_0002 VISTA 19:10121785-10724671

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003684 IEA damaged DNA binding
GO:0005515 IEA protein binding
GO:0005615 IEA extracellular space
GO:0005634 ISS nucleus
GO:0005737 ISS cytoplasm
GO:0016055 IDA Wnt signaling pathway
GO:0031464 ISS Cul4A-RING E3 ubiquitin ligase complex
GO:0031465 ISS Cul4B-RING E3 ubiquitin ligase complex
GO:0035518 IEA histone H2A monoubiquitination
GO:0042787 IEA protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0043066 IMP negative regulation of apoptotic process
GO:0043161 ISS proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070062 IEA extracellular vesicular exosome
GO:0070914 IEA UV-damage excision repair
GO:0080008 ISS Cul4-RING E3 ubiquitin ligase complex
GO:1901990 IEA regulation of mitotic cell cycle phase transition

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074431 ddb1 damage specific DNA binding protein 1 protein_coding Danio_rerio
ENSDARG00000089106 ddb1 damage specific DNA binding protein 1 protein_coding Danio_rerio
ENSG00000167986 DDB1 damage-specific DNA binding protein 1, 127kDa protein_coding Homo_sapiens

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