C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: PDZ binding kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000168078 PBK 9606 - 8:27809620-27838095 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000301905 PBK-001 27809620-27838095 protein_coding
  ENST00000521226 PBK-005 27820604-27837809 nonsense_mediated_decay
  ENST00000522944 PBK-002 27810201-27838082 protein_coding
  ENST00000524266 PBK-006 27810294-27837783 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000301905ENST00000521226ENST00000522944ENST00000524266
Transcript ID Adipose Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000301905 0.025±0.00 0.007±0.00 N/A 0.648±0.38 0.011±0.00 N/A 0.024±0.00 N/A N/A 1.681±1.19 1.451±0.98 14.883±8.07
ENST00000521226 N/A N/A 0.926±0.00 0.601±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000522944 N/A N/A N/A 0.506±0.00 0.007±0.00 N/A N/A N/A N/A 1.963±0.00 1.062±0.00 6.954±0.00
ENST00000524266 N/A 0.034±0.00 N/A N/A 0.019±0.00 0.164±0.00 N/A 0.091±0.00 0.778±0.00 1.726±1.22 N/A 7.353±1.21

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009DK CIL_0009DK_0001 VISTA 8:27594923-28195834
CIL_0005SU CIL_0005SU_0002 CGP 8:27733311-27812640
CIL_00073A CIL_00073A_0002 CGP 8:27771949-27838095

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001933 IEA negative regulation of protein phosphorylation
GO:0004672 IEA protein kinase activity
GO:0004674 TAS protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005575 ND cellular_component
GO:0006468 IEA protein phosphorylation
GO:0007067 NAS mitotic nuclear division
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0032435 IEA negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032873 IEA negative regulation of stress-activated MAPK cascade
GO:0034644 IEA cellular response to UV
GO:0050728 IEA negative regulation of inflammatory response

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007221 pbk PDZ binding kinase protein_coding Danio_rerio
ENSMUSG00000022033 Pbk PDZ binding kinase protein_coding Mus_musculus

Loading