C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: PDZ binding kinase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022033 Pbk 10090 + 14:65805837-65817822 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000022612 Pbk-001 65805837-65817822 protein_coding
  ENSMUST00000139644 Pbk-003 65806232-65813874 protein_coding
  ENSMUST00000152130 Pbk-002 65805937-65813108 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000022612ENSMUST00000139644ENSMUST00000152130
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000022612 1.861±1.66 0.741±0.25 0.543±0.23 8.649±7.49 0.433±0.12 1.988±1.24 0.114±0.03 0.198±0.08 11.092±10.13 0.609±0.00 0.057±0.03 3.364±1.72 11.005±3.75 17.560±6.85
ENSMUST00000139644 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.119±0.00 10.946±0.00 13.615±11.99 23.062±0.00
ENSMUST00000152130 N/A 0.907±0.68 N/A N/A 0.139±0.00 N/A N/A N/A N/A N/A 0.098±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009DK CIL_0009DK_0002 VISTA 14:65449305-66050499

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001933 IMP negative regulation of protein phosphorylation
GO:0004674 ISO protein serine/threonine kinase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005575 ND cellular_component
GO:0018105 ISO peptidyl-serine phosphorylation
GO:0018107 ISO peptidyl-threonine phosphorylation
GO:0032435 IMP negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032873 IMP negative regulation of stress-activated MAPK cascade
GO:0034644 IMP cellular response to UV
GO:0050728 IMP negative regulation of inflammatory response

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007221 pbk PDZ binding kinase protein_coding Danio_rerio
ENSG00000168078 PBK PDZ binding kinase protein_coding Homo_sapiens

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