C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: pancreas specific transcription factor, 1a
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000168267 PTF1A 9606 + 10:23192327-23194252 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000376504 PTF1A-001 23192327-23194252 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainOvaryTestisENST00000376504
Transcript ID Brain Ovary Testis
ENST00000376504 0.164±0.00 0.105±0.00 1.258±0.65

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00088N CIL_00088N_0001 VISTA 10:22901909-23502579
CIL_0002D0 CIL_0002D0_0001 CGP 10:23095506-23194252
CIL_000782 CIL_000782_0002 CGP 10:23192327-23344845

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 ISS DNA binding
GO:0003682 IEA chromatin binding
GO:0005515 IEA protein binding
GO:0005622 IEA intracellular
GO:0005634 ISS nucleus
GO:0005667 ISS transcription factor complex
GO:0005737 ISS cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 ISS regulation of transcription, DNA-templated
GO:0009790 IEA embryo development
GO:0009888 IDA tissue development
GO:0010842 ISS retina layer formation
GO:0021549 IMP cerebellum development
GO:0030154 IEA cell differentiation
GO:0030902 IEA hindbrain development
GO:0031016 IMP pancreas development
GO:0031017 ISS exocrine pancreas development
GO:0031018 TAS endocrine pancreas development
GO:0035881 ISS amacrine cell differentiation
GO:0043565 IEA sequence-specific DNA binding
GO:0045165 IEA cell fate commitment
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046983 IEA protein dimerization activity
GO:0048384 IEA retinoic acid receptor signaling pathway
GO:0048663 IEA neuron fate commitment
GO:0048699 IEA generation of neurons
GO:0060042 IEA retina morphogenesis in camera-type eye
GO:0061074 ISS regulation of neural retina development
GO:0070888 IEA E-box binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000014479 ptf1a pancreas specific transcription factor, 1a protein_coding Danio_rerio
ENSMUSG00000026735 Ptf1a pancreas specific transcription factor, 1a protein_coding Mus_musculus

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