C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: interferon regulatory factor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000168310 IRF2 9606 - 4:184387713-184474580 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000393593 IRF2-001 184387713-184474580 protein_coding
  ENST00000502750 IRF2-010 184389040-184418631 protein_coding
  ENST00000504340 IRF2-003 184448656-184474548 processed_transcript
  ENST00000505067 IRF2-009 184389022-184418590 protein_coding
  ENST00000506230 IRF2-004 184418167-184474186 protein_coding
  ENST00000507523 IRF2-005 184408158-184474049 protein_coding
  ENST00000509274 IRF2-006 184418175-184474047 nonsense_mediated_decay
  ENST00000510814 IRF2-007 184408205-184474048 protein_coding
  ENST00000512020 IRF2-008 184408159-184474548 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000393593ENST00000504340ENST00000512020
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000393593 13.802±0.00 9.781±0.00 5.801±0.00 5.712±0.84 7.900±0.09 10.979±3.96 3.406±0.37 7.866±4.59 6.644±2.30 15.021±4.89 9.820±0.00 8.960±2.01 10.119±2.28 5.524±3.89
ENST00000504340 N/A N/A N/A N/A N/A 5.710±0.00 N/A 8.996±0.00 N/A N/A N/A N/A N/A N/A
ENST00000512020 N/A N/A 5.120±0.00 N/A N/A 3.385±0.00 2.967±0.00 N/A 6.878±0.00 13.264±0.00 8.505±0.00 7.249±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00094W CIL_00094W_0001 VISTA 4:184083896-184687060
CIL_0000GS CIL_0000GS_0002 CGP 4:184088706-184474580
CIL_00097G CIL_00097G_0001 VISTA 4:184147184-184748475
CIL_0000GX CIL_0000GX_0002 CGP 4:184387713-184649509

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 TAS negative regulation of transcription from RNA polymerase II promoter
GO:0000975 IEA regulatory region DNA binding
GO:0003677 IDA DNA binding
GO:0003700 IEA:IMP sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005654 TAS nucleoplasm
GO:0005829 TAS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA:IMP regulation of transcription, DNA-templated
GO:0007596 TAS blood coagulation
GO:0008283 TAS cell proliferation
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0060333 TAS interferon-gamma-mediated signaling pathway
GO:0060337 TAS type I interferon signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007387 irf2a interferon regulatory factor 2a protein_coding Danio_rerio
ENSDARG00000040465 IRF2 (2 of 2) interferon regulatory factor 2 protein_coding Danio_rerio
ENSMUSG00000031627 Irf2 interferon regulatory factor 2 protein_coding Mus_musculus

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