C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: chemokine (C-X3-C motif) receptor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000168329 CX3CR1 9606 - 3:39263494-39281735 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000358309 CX3CR1-201 39263495-39281735 protein_coding
  ENST00000399220 CX3CR1-001 39263494-39280034 protein_coding
  ENST00000412814 CX3CR1-004 39266191-39281273 protein_coding
  ENST00000435290 CX3CR1-003 39266011-39280439 protein_coding
  ENST00000541347 CX3CR1-202 39263495-39281273 protein_coding
  ENST00000542107 CX3CR1-203 39263495-39280439 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000358309ENST00000399220ENST00000412814ENST00000541347
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000358309 N/A N/A N/A 4.418±0.00 0.255±0.00 N/A N/A N/A N/A 0.530±0.16 N/A 0.431±0.00 0.642±0.00 N/A
ENST00000399220 0.136±0.00 0.306±0.00 0.281±0.00 3.279±0.72 0.775±0.28 0.081±0.05 0.220±0.03 0.294±0.05 0.374±0.29 0.545±0.12 0.315±0.11 0.897±0.75 1.930±1.20 0.584±0.27
ENST00000412814 N/A N/A N/A N/A 0.417±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000541347 N/A 0.325±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002282 IEA microglial cell activation involved in immune response
GO:0004896 IEA cytokine receptor activity
GO:0004930 IEA G-protein coupled receptor activity
GO:0004950 TAS chemokine receptor activity
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006935 TAS chemotaxis
GO:0006968 TAS cellular defense response
GO:0007155 IEA cell adhesion
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0009611 TAS response to wounding
GO:0016021 IEA integral component of membrane
GO:0016032 IEA viral process
GO:0016495 IEA C-X3-C chemokine receptor activity
GO:0016525 IEA negative regulation of angiogenesis
GO:0019221 IEA cytokine-mediated signaling pathway
GO:0021795 IEA cerebral cortex cell migration
GO:0030336 IEA negative regulation of cell migration
GO:0032809 IEA neuronal cell body membrane
GO:0043005 IEA neuron projection
GO:0045766 IEA positive regulation of angiogenesis
GO:0048246 IEA macrophage chemotaxis
GO:0048471 IEA perinuclear region of cytoplasm
GO:0070098 IEA chemokine-mediated signaling pathway
GO:0071222 IEA cellular response to lipopolysaccharide
GO:0071560 IEA cellular response to transforming growth factor beta stimulus
GO:2001240 IEA negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000032826 ccr8.1 chemokine (C-C motif) receptor 8.1 protein_coding Danio_rerio
ENSDARG00000086616 CABZ01093075.1 Uncharacterized protein protein_coding Danio_rerio
ENSDARG00000095789 ccr8.1 chemokine (C-C motif) receptor 8.1 protein_coding Danio_rerio
ENSMUSG00000052336 Cx3cr1 chemokine (C-X3-C motif) receptor 1 protein_coding Mus_musculus

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