C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: chemokine (C-X3-C motif) receptor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000052336 Cx3cr1 10090 - 9:119901616-120068283 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000064165 Cx3cr1-201 120048693-120068282 protein_coding
  ENSMUST00000177637 Cx3cr1-202 119901616-120068283 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000064165ENSMUST00000177637
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000064165 0.735±0.55 2.968±1.32 0.483±0.01 1.067±0.35 0.416±0.15 0.731±0.00 0.382±0.08 0.571±0.20 0.455±0.26 0.755±0.07 0.085±0.05 2.570±1.53 0.368±0.20 0.239±0.13
ENSMUST00000177637 6.049±5.21 6.548±2.02 0.802±0.07 1.268±0.52 3.139±0.46 5.965±1.27 1.454±0.07 2.092±0.26 0.567±0.35 5.317±0.33 0.020±0.01 5.747±3.02 0.483±0.35 1.087±0.29

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006H1 CIL_0006H1_0002 CGP 9:119753763-119926579

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002282 IMP microglial cell activation involved in immune response
GO:0004896 IMP cytokine receptor activity
GO:0005515 IEA protein binding
GO:0007155 IEA cell adhesion
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0016021 IEA integral component of membrane
GO:0016495 IEA C-X3-C chemokine receptor activity
GO:0016525 IMP negative regulation of angiogenesis
GO:0019221 IMP cytokine-mediated signaling pathway
GO:0021795 IMP cerebral cortex cell migration
GO:0030336 IEA negative regulation of cell migration
GO:0032809 IEA neuronal cell body membrane
GO:0043005 IEA neuron projection
GO:0045766 IEA positive regulation of angiogenesis
GO:0048246 IMP macrophage chemotaxis
GO:0048471 IEA perinuclear region of cytoplasm
GO:0070098 IEA chemokine-mediated signaling pathway
GO:0071222 IEA cellular response to lipopolysaccharide
GO:0071560 IEA cellular response to transforming growth factor beta stimulus
GO:2001240 IMP negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000032826 ccr8.1 chemokine (C-C motif) receptor 8.1 protein_coding Danio_rerio
ENSDARG00000086616 CABZ01093075.1 Uncharacterized protein protein_coding Danio_rerio
ENSDARG00000095789 ccr8.1 chemokine (C-C motif) receptor 8.1 protein_coding Danio_rerio
ENSG00000168329 CX3CR1 chemokine (C-X3-C motif) receptor 1 protein_coding Homo_sapiens

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