C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ADP-ribosylation factor 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000168374 ARF4 9606 - 3:57571363-57598220 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000303436 ARF4-001 57571363-57597408 protein_coding
  ENST00000463880 ARF4-006 57575623-57597508 protein_coding
  ENST00000483848 ARF4-005 57575548-57597198 processed_transcript
  ENST00000486310 ARF4-002 57571405-57597366 nonsense_mediated_decay
  ENST00000488156 ARF4-009 57597074-57598220 protein_coding
  ENST00000489843 ARF4-003 57571398-57597334 protein_coding
  ENST00000493378 ARF4-008 57583925-57597404 processed_transcript
  ENST00000495354 ARF4-007 57596606-57597368 processed_transcript
  ENST00000496292 ARF4-004 57571392-57597325 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000303436ENST00000463880ENST00000486310ENST00000489843ENST00000496292
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000303436 22.289±0.00 34.522±0.00 4.995±0.00 20.602±7.62 38.172±15.79 28.795±7.23 14.801±10.63 37.034±24.26 30.870±17.22 45.288±31.01 5.793±4.09 47.549±32.95 96.446±52.47 35.824±16.18
ENST00000463880 40.031±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 140.717±0.00 257.541±0.00 147.689±0.00
ENST00000486310 N/A N/A N/A N/A N/A N/A 1.148±0.00 N/A N/A N/A N/A 18.656±0.00 N/A 12.460±0.00
ENST00000489843 N/A N/A N/A 11.340±0.00 N/A 10.718±0.00 N/A 15.631±0.00 16.105±0.00 N/A 2.027±0.52 21.292±0.00 N/A N/A
ENST00000496292 N/A 7.924±0.00 1.431±0.00 N/A 20.843±0.00 8.360±0.00 N/A N/A N/A N/A 3.509±0.00 N/A 25.438±0.00 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003924 IEA GTPase activity
GO:0004871 IEA signal transducer activity
GO:0005154 IDA epidermal growth factor receptor binding
GO:0005515 IPI protein binding
GO:0005525 IEA:IDA GTP binding
GO:0005622 IEA intracellular
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005794 IEA Golgi apparatus
GO:0005829 IDA cytosol
GO:0005886 IEA plasma membrane
GO:0006471 IDA protein ADP-ribosylation
GO:0006886 IEA intracellular protein transport
GO:0007173 IEA epidermal growth factor receptor signaling pathway
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007264 IEA small GTPase mediated signal transduction
GO:0007420 IEA brain development
GO:0015031 IEA protein transport
GO:0016020 IDA membrane
GO:0016192 IEA vesicle-mediated transport
GO:0016477 IDA cell migration
GO:0019001 IEA guanyl nucleotide binding
GO:0031584 IDA activation of phospholipase D activity
GO:0031683 IEA G-protein beta/gamma-subunit complex binding
GO:0032587 IDA ruffle membrane
GO:0043066 IDA negative regulation of apoptotic process
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048678 IEA response to axon injury
GO:0070062 IDA extracellular vesicular exosome
GO:2000377 IDA regulation of reactive oxygen species metabolic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042382 ARF5 (1 of 2) ADP-ribosylation factor 4 protein_coding Danio_rerio
ENSDARG00000045989 arf4a ADP-ribosylation factor 4a protein_coding Danio_rerio
ENSDARG00000070472 arf5 ADP-ribosylation factor 5 protein_coding Danio_rerio
ENSMUSG00000021877 Arf4 ADP-ribosylation factor 4 protein_coding Mus_musculus

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