C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ring finger and WD repeat domain 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000168411 RFWD3 9606 - 16:74621394-74666881 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000361070 RFWD3-001 74621394-74666881 protein_coding
  ENST00000571750 RFWD3-002 74623429-74666870 protein_coding
  ENST00000571776 RFWD3-007 74660600-74666869 retained_intron
  ENST00000572337 RFWD3-012 74644620-74666859 protein_coding
  ENST00000572610 RFWD3-004 74643979-74644637 retained_intron
  ENST00000572840 RFWD3-003 74664335-74666832 retained_intron
  ENST00000572990 RFWD3-010 74660998-74666874 protein_coding
  ENST00000575113 RFWD3-009 74661101-74666537 protein_coding
  ENST00000575154 RFWD3-005 74628508-74632733 retained_intron
  ENST00000575281 RFWD3-006 74637876-74649243 retained_intron
  ENST00000575397 RFWD3-008 74660780-74666832 retained_intron
  ENST00000576652 RFWD3-011 74661082-74666839 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000361070ENST00000571750ENST00000575397
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000361070 2.009±0.00 1.957±0.00 N/A 0.798±0.32 1.962±0.43 0.899±0.00 0.370±0.10 0.418±0.00 0.233±0.00 0.692±0.00 0.086±0.00 1.665±0.81 2.828±2.00 13.453±1.81
ENST00000571750 N/A N/A 0.322±0.00 0.463±0.00 N/A 1.406±0.00 N/A 0.119±0.00 N/A 0.685±0.00 0.225±0.00 0.818±0.00 N/A N/A
ENST00000575397 N/A N/A N/A N/A N/A N/A N/A 1.007±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002I2 CIL_0002I2_0001 CGP 16:74451958-74666881
CIL_0002PQ CIL_0002PQ_0001 CGP 16:74621394-74700960

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002039 IPI p53 binding
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IEA cytoplasm
GO:0006281 IEA DNA repair
GO:0008270 IEA zinc ion binding
GO:0010212 IDA response to ionizing radiation
GO:0016567 IEA protein ubiquitination
GO:0016874 IEA ligase activity
GO:0031571 IMP mitotic G1 DNA damage checkpoint
GO:0035861 IDA site of double-strand break
GO:0046872 IEA metal ion binding
GO:0097371 IPI MDM2/MDM4 family protein binding
GO:2000001 IMP regulation of DNA damage checkpoint

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000087752 rfwd3 ring finger and WD repeat domain 3 protein_coding Danio_rerio
ENSMUSG00000033596 Rfwd3 ring finger and WD repeat domain 3 protein_coding Mus_musculus

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