C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: collagen, type IV, alpha 3 (Goodpasture antigen)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000169031 COL4A3 9606 + 2:227164565-227314792 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000304990 COL4A3-004 227289158-227294204 protein_coding
  ENST00000396578 COL4A3-001 227164565-227314792 protein_coding
  ENST00000468753 COL4A3-005 227296299-227303900 processed_transcript
  ENST00000469504 COL4A3-002 227307772-227311870 processed_transcript
  ENST00000471862 COL4A3-006 227297691-227304328 retained_intron
  ENST00000487633 COL4A3-003 227284304-227291039 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBreastHeartKidneyLiverLungMuscleENST00000396578
Transcript ID Adrenal Bladder Breast Heart Kidney Liver Lung Muscle
ENST00000396578 2.845±0.00 4.192±0.00 0.473±0.00 1.300±0.91 11.826±0.00 0.493±0.00 3.102±1.02 1.490±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004AI CIL_0004AI_0002 CGP 2:227002711-227314792
CIL_0006XR CIL_0006XR_0001 CGP 2:227164565-227357836

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005178 TAS integrin binding
GO:0005198 NAS structural molecule activity
GO:0005201 IEA extracellular matrix structural constituent
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005581 IEA collagen trimer
GO:0005587 IDA collagen type IV trimer
GO:0005604 IDA basement membrane
GO:0005788 TAS endoplasmic reticulum lumen
GO:0006919 IDA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007155 IEA cell adhesion
GO:0007166 NAS cell surface receptor signaling pathway
GO:0007411 TAS axon guidance
GO:0007605 TAS sensory perception of sound
GO:0008015 TAS blood circulation
GO:0008191 NAS metalloendopeptidase inhibitor activity
GO:0008283 IDA cell proliferation
GO:0008285 TAS negative regulation of cell proliferation
GO:0010951 NAS negative regulation of endopeptidase activity
GO:0016525 IDA negative regulation of angiogenesis
GO:0022617 TAS extracellular matrix disassembly
GO:0030198 TAS extracellular matrix organization
GO:0030574 TAS collagen catabolic process
GO:0032836 ISS glomerular basement membrane development
GO:0072577 IDA endothelial cell apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003395 col4a3 collagen, type IV, alpha 3 protein_coding Danio_rerio
ENSMUSG00000079465 Col4a3 collagen, type IV, alpha 3 protein_coding Mus_musculus

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