C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: collagen, type IV, alpha 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000079465 Col4a3 10090 + 1:82586921-82722059 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000113457 Col4a3-001 82586976-82722059 protein_coding
  ENSMUST00000125563 Col4a3-002 82715304-82718884 nonsense_mediated_decay
  ENSMUST00000141994 Col4a3-004 82586921-82642853 retained_intron
  ENSMUST00000152664 Col4a3-003 82715304-82718982 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeKidneyLungOvaryTestisENSMUST00000113457
Transcript ID Adipose Kidney Lung Ovary Testis
ENSMUST00000113457 1.441±0.02 28.320±1.86 24.901±0.75 1.499±0.55 2.655±0.29

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004AI CIL_0004AI_0003 CGP 1:82448423-82722059
CIL_0006XR CIL_0006XR_0002 CGP 1:82586921-82752394

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005178 ISS integrin binding
GO:0005201 IEA extracellular matrix structural constituent
GO:0005515 IEA protein binding
GO:0005587 IDA collagen type IV trimer
GO:0005604 ISS basement membrane
GO:0006919 ISS activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007155 IEA cell adhesion
GO:0007166 IDA cell surface receptor signaling pathway
GO:0008283 ISS cell proliferation
GO:0016525 IDA negative regulation of angiogenesis
GO:0032836 IMP glomerular basement membrane development
GO:0072577 ISS endothelial cell apoptotic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003395 col4a3 collagen, type IV, alpha 3 protein_coding Danio_rerio
ENSG00000169031 COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) protein_coding Homo_sapiens

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