C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: androgen receptor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000169083 AR 9606 + X:67544032-67730619 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000374690 AR-001 67544623-67730619 protein_coding
  ENST00000396043 AR-002 67568889-67724288 protein_coding
  ENST00000396044 AR-201 67544032-67730618 protein_coding
  ENST00000504326 AR-004 67544820-67696075 protein_coding
  ENST00000513847 AR-003 67544820-67689763 processed_transcript
  ENST00000514029 AR-005 67544820-67696075 nonsense_mediated_decay
  ENST00000612010 AR-202 67544820-67696075 protein_coding
  ENST00000612452 AR-203 67544032-67730618 protein_coding
  ENST00000613054 AR-204 67544820-67696075 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000374690ENST00000396043ENST00000396044ENST00000513847ENST00000612452
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000374690 1.386±0.00 N/A 0.473±0.00 0.097±0.00 1.338±1.08 0.388±0.00 0.804±0.19 11.807±0.00 2.267±1.09 0.559±0.21 0.989±0.00 2.127±1.43 0.187±0.00 2.038±0.48
ENST00000396043 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.530±0.00 N/A N/A N/A
ENST00000396044 N/A 0.112±0.00 N/A N/A N/A N/A N/A 0.818±0.00 N/A N/A 0.797±0.00 N/A 0.054±0.02 N/A
ENST00000513847 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.038±0.00 N/A
ENST00000612452 0.947±0.00 N/A 0.669±0.00 0.080±0.00 0.808±0.00 0.315±0.00 0.734±0.00 3.953±0.00 0.565±0.00 0.112±0.00 N/A 0.811±0.00 N/A 1.165±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002RO CIL_0002RO_0001 CGP X:66595637-67730619
CIL_0001SR CIL_0001SR_0002 CGP X:67544032-68433913

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000790 IDA nuclear chromatin
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001085 IPI RNA polymerase II transcription factor binding
GO:0001701 IEA in utero embryonic development
GO:0003073 IEA regulation of systemic arterial blood pressure
GO:0003382 IEA epithelial cell morphogenesis
GO:0003677 IEA DNA binding
GO:0003682 IDA chromatin binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003707 IEA steroid hormone receptor activity
GO:0004879 IDA ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0004882 IEA androgen receptor activity
GO:0005102 IEA receptor binding
GO:0005496 IEA steroid binding
GO:0005497 IEA androgen binding
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0005886 IEA plasma membrane
GO:0006351 IDA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0006367 TAS transcription initiation from RNA polymerase II promoter
GO:0006810 TAS transport
GO:0007165 TAS signal transduction
GO:0007267 TAS cell-cell signaling
GO:0007283 IEA spermatogenesis
GO:0007338 IEA single fertilization
GO:0007548 NAS sex differentiation
GO:0008013 IDA beta-catenin binding
GO:0008134 IPI transcription factor binding
GO:0008219 IEA cell death
GO:0008270 IEA zinc ion binding
GO:0008283 NAS cell proliferation
GO:0008284 IDA positive regulation of cell proliferation
GO:0008584 IEA male gonad development
GO:0009566 IEA fertilization
GO:0009987 IEA cellular process
GO:0010467 TAS gene expression
GO:0010468 IEA regulation of gene expression
GO:0016049 NAS cell growth
GO:0019102 IEA male somatic sex determination
GO:0019899 IEA enzyme binding
GO:0019904 IEA protein domain specific binding
GO:0030424 IEA axon
GO:0030425 IEA dendrite
GO:0030521 IEA androgen receptor signaling pathway
GO:0030522 IDA intracellular receptor signaling pathway
GO:0030850 NAS prostate gland development
GO:0032868 IEA response to insulin
GO:0033148 IEA positive regulation of intracellular estrogen receptor signaling pathway
GO:0033327 IEA Leydig cell differentiation
GO:0035264 IEA multicellular organism growth
GO:0042327 IMP positive regulation of phosphorylation
GO:0043234 IDA protein complex
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043410 IEA positive regulation of MAPK cascade
GO:0043565 IEA sequence-specific DNA binding
GO:0043568 IEA positive regulation of insulin-like growth factor receptor signaling pathway
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045720 IDA negative regulation of integrin biosynthetic process
GO:0045726 IDA positive regulation of integrin biosynthetic process
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0045945 IDA positive regulation of transcription from RNA polymerase III promoter
GO:0046661 IEA male sex differentiation
GO:0046983 NAS protein dimerization activity
GO:0048608 IEA reproductive structure development
GO:0048638 IEA regulation of developmental growth
GO:0048645 IEA organ formation
GO:0048808 IEA male genitalia morphogenesis
GO:0050680 IEA negative regulation of epithelial cell proliferation
GO:0050681 IEA androgen receptor binding
GO:0050790 IEA regulation of catalytic activity
GO:0051092 IMP positive regulation of NF-kappaB transcription factor activity
GO:0051259 IDA protein oligomerization
GO:0060520 IEA activation of prostate induction by androgen receptor signaling pathway
GO:0060571 IEA morphogenesis of an epithelial fold
GO:0060599 IEA lateral sprouting involved in mammary gland duct morphogenesis
GO:0060685 IEA regulation of prostatic bud formation
GO:0060736 IEA prostate gland growth
GO:0060740 IEA prostate gland epithelium morphogenesis
GO:0060742 IEA epithelial cell differentiation involved in prostate gland development
GO:0060748 IEA tertiary branching involved in mammary gland duct morphogenesis
GO:0060749 IEA mammary gland alveolus development
GO:0061458 IEA reproductive system development
GO:0070974 IEA POU domain binding
GO:0071383 IEA cellular response to steroid hormone stimulus
GO:0072520 IEA seminiferous tubule development
GO:0090003 IDA regulation of establishment of protein localization to plasma membrane
GO:2001237 IDA negative regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000067976 ar androgen receptor protein_coding Danio_rerio
ENSMUSG00000046532 Ar androgen receptor protein_coding Mus_musculus

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