C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: androgen receptor
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000046532 Ar 10090 + X:98149721-98323215 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000052837 Ar-001 98149721-98323215 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000052837
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000052837 4.529±2.41 10.256±3.32 1.244±1.04 0.648±0.89 1.732±0.42 0.158±0.02 0.332±0.02 2.635±0.26 0.221±0.18 0.852±0.07 3.705±1.09 5.439±2.67 0.118±0.24 0.423±0.15

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002RO CIL_0002RO_0002 CGP X:97333840-98323215
CIL_0001SR CIL_0001SR_0003 CGP X:98149721-98891025

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000790 ISS nuclear chromatin
GO:0001701 IMP in utero embryonic development
GO:0003073 IGI regulation of systemic arterial blood pressure
GO:0003382 IGI epithelial cell morphogenesis
GO:0003700 ISS sequence-specific DNA binding transcription factor activity
GO:0004879 ISS ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0004882 ISS androgen receptor activity
GO:0005102 IEA receptor binding
GO:0005497 IEA androgen binding
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005737 ISS cytoplasm
GO:0005886 IDA plasma membrane
GO:0006351 ISS transcription, DNA-templated
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006357 IMP regulation of transcription from RNA polymerase II promoter
GO:0007283 IMP spermatogenesis
GO:0007338 IGI single fertilization
GO:0008013 ISS beta-catenin binding
GO:0008270 IEA zinc ion binding
GO:0008284 ISS positive regulation of cell proliferation
GO:0008584 IMP male gonad development
GO:0009566 IMP fertilization
GO:0009987 IDA cellular process
GO:0010468 IMP regulation of gene expression
GO:0019102 IMP male somatic sex determination
GO:0019899 IPI enzyme binding
GO:0019904 IEA protein domain specific binding
GO:0030424 IEA axon
GO:0030425 IEA dendrite
GO:0030521 IDA androgen receptor signaling pathway
GO:0030522 ISS intracellular receptor signaling pathway
GO:0032868 IEA response to insulin
GO:0033148 IMP positive regulation of intracellular estrogen receptor signaling pathway
GO:0033327 IMP Leydig cell differentiation
GO:0035264 IGI multicellular organism growth
GO:0042327 ISS positive regulation of phosphorylation
GO:0043234 ISO protein complex
GO:0043401 IEA steroid hormone mediated signaling pathway
GO:0043410 IMP positive regulation of MAPK cascade
GO:0043565 IDA sequence-specific DNA binding
GO:0043568 IMP positive regulation of insulin-like growth factor receptor signaling pathway
GO:0044212 ISS transcription regulatory region DNA binding
GO:0045720 ISS negative regulation of integrin biosynthetic process
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0046661 IEA male sex differentiation
GO:0048608 IMP reproductive structure development
GO:0048638 IMP regulation of developmental growth
GO:0048645 IMP organ formation
GO:0048808 IMP male genitalia morphogenesis
GO:0050680 IMP negative regulation of epithelial cell proliferation
GO:0050681 IEA androgen receptor binding
GO:0050790 IMP regulation of catalytic activity
GO:0051092 ISS positive regulation of NF-kappaB transcription factor activity
GO:0051259 ISO protein oligomerization
GO:0060520 IMP activation of prostate induction by androgen receptor signaling pathway
GO:0060571 IMP morphogenesis of an epithelial fold
GO:0060599 IMP lateral sprouting involved in mammary gland duct morphogenesis
GO:0060685 IGI regulation of prostatic bud formation
GO:0060736 IMP prostate gland growth
GO:0060740 IMP prostate gland epithelium morphogenesis
GO:0060742 IMP epithelial cell differentiation involved in prostate gland development
GO:0060748 IMP tertiary branching involved in mammary gland duct morphogenesis
GO:0060749 IMP mammary gland alveolus development
GO:0061458 IGI reproductive system development
GO:0070974 IDA POU domain binding
GO:0071383 IEA cellular response to steroid hormone stimulus
GO:0072520 IMP seminiferous tubule development
GO:0090003 ISS regulation of establishment of protein localization to plasma membrane
GO:2001237 ISS negative regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000067976 ar androgen receptor protein_coding Danio_rerio
ENSG00000169083 AR androgen receptor protein_coding Homo_sapiens

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