C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: actin filament associated protein 1-like 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000169129 AFAP1L2 9606 - 10:114294824-114404756 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000304129 AFAP1L2-002 114294824-114404485 protein_coding
  ENST00000369271 AFAP1L2-001 114294824-114404756 protein_coding
  ENST00000419268 AFAP1L2-006 114310354-114404480 protein_coding
  ENST00000483496 AFAP1L2-007 114323177-114404488 processed_transcript
  ENST00000486300 AFAP1L2-004 114300516-114305133 processed_transcript
  ENST00000491814 AFAP1L2-003 114294826-114302017 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000304129ENST00000369271ENST00000419268ENST00000483496ENST00000491814
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000304129 2.250±0.00 2.559±0.00 1.138±0.00 1.569±0.68 2.304±0.00 4.347±0.00 1.200±0.00 4.025±3.91 0.559±0.00 N/A 0.818±0.00 3.767±2.46 7.137±1.38 2.590±2.03
ENST00000369271 N/A 1.797±0.00 N/A 0.536±0.15 0.784±0.38 N/A 0.263±0.00 2.265±0.00 0.854±0.00 2.252±0.00 N/A 3.142±1.01 2.593±0.91 0.282±0.00
ENST00000419268 N/A N/A 1.062±0.00 N/A N/A N/A N/A 1.181±0.00 1.869±0.00 1.004±0.00 N/A N/A N/A N/A
ENST00000483496 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.086±0.00 4.888±0.00 N/A N/A
ENST00000491814 N/A N/A N/A 0.310±0.00 N/A N/A N/A N/A N/A 0.189±0.00 N/A 1.380±0.00 N/A 0.533±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002OI CIL_0002OI_0001 CGP 10:114239330-114404756
CIL_0002OJ CIL_0002OJ_0001 CGP 10:114294824-114685003

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005737 IDA cytoplasm
GO:0006954 IDA inflammatory response
GO:0007346 IDA regulation of mitotic cell cycle
GO:0017124 IPI SH3 domain binding
GO:0030296 IDA protein tyrosine kinase activator activity
GO:0032675 IDA regulation of interleukin-6 production
GO:0032757 IDA positive regulation of interleukin-8 production
GO:0042169 IPI SH2 domain binding
GO:0045742 IDA positive regulation of epidermal growth factor receptor signaling pathway
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0061098 IDA positive regulation of protein tyrosine kinase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074806 afap1l2 actin filament associated protein 1-like 2 protein_coding Danio_rerio
ENSMUSG00000025083 Afap1l2 actin filament associated protein 1-like 2 protein_coding Mus_musculus

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