C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: actin filament associated protein 1-like 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025083 Afap1l2 10090 - 19:56912361-57008228 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000111584 Afap1l2-003 56912361-57008210 protein_coding
  ENSMUST00000118800 Afap1l2-005 56912361-57008198 protein_coding
  ENSMUST00000122359 Afap1l2-001 56912361-57008228 protein_coding
  ENSMUST00000126964 Afap1l2-006 56930098-57001046 protein_coding
  ENSMUST00000132851 Afap1l2-004 56942475-57008208 retained_intron
  ENSMUST00000148049 Afap1l2-002 56923540-57008228 protein_coding
  ENSMUST00000155467 Afap1l2-007 56920398-56928553 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000111584ENSMUST00000118800ENSMUST00000122359
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000111584 1.670±0.09 1.158±0.54 0.654±0.00 N/A N/A 1.027±0.41 0.153±0.00 1.186±0.41 0.087±0.00 1.063±0.20 N/A 2.078±0.64 N/A N/A
ENSMUST00000118800 3.769±2.17 1.182±0.31 3.266±0.14 1.419±0.49 1.233±0.31 1.102±0.48 0.494±0.14 3.177±1.08 0.292±0.19 2.444±0.43 0.370±0.16 6.853±2.55 53.902±43.27 0.137±0.03
ENSMUST00000122359 1.282±0.00 0.703±0.00 N/A N/A 0.321±0.00 N/A 0.291±0.00 0.667±0.00 N/A N/A N/A 1.563±0.44 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002OI CIL_0002OI_0002 CGP 19:56874249-57008228
CIL_0002OJ CIL_0002OJ_0002 CGP 19:56912361-57314919

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005737 IEA cytoplasm
GO:0006954 IEA inflammatory response
GO:0007346 IEA regulation of mitotic cell cycle
GO:0017124 IEA SH3 domain binding
GO:0030296 IEA protein tyrosine kinase activator activity
GO:0032675 IEA regulation of interleukin-6 production
GO:0032757 IEA positive regulation of interleukin-8 production
GO:0042169 IEA SH2 domain binding
GO:0045742 IEA positive regulation of epidermal growth factor receptor signaling pathway
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0061098 IEA positive regulation of protein tyrosine kinase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074806 afap1l2 actin filament associated protein 1-like 2 protein_coding Danio_rerio
ENSG00000169129 AFAP1L2 actin filament associated protein 1-like 2 protein_coding Homo_sapiens

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