C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: neuroligin 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000169992 NLGN2 9606 + 17:7404874-7419860 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000302926 NLGN2-001 7408183-7419860 protein_coding
  ENST00000570940 NLGN2-005 7408641-7415128 protein_coding
  ENST00000572893 NLGN2-004 7405356-7408509 processed_transcript
  ENST00000575301 NLGN2-002 7404874-7418684 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000302926ENST00000570940ENST00000575301
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000302926 7.694±0.00 3.266±0.00 N/A 22.437±19.92 2.655±2.49 5.020±4.75 1.356±1.25 3.430±3.35 0.934±0.23 4.404±3.95 1.417±1.04 17.930±18.68 2.410±1.05 6.479±2.82
ENST00000570940 N/A N/A 0.375±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000575301 N/A N/A 0.193±0.00 N/A 0.580±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002087 ISS regulation of respiratory gaseous exchange by neurological system process
GO:0004872 IBA receptor activity
GO:0005515 IEA protein binding
GO:0005887 ISS integral component of plasma membrane
GO:0007158 ISS neuron cell-cell adhesion
GO:0007416 ISS synapse assembly
GO:0008152 IEA metabolic process
GO:0009986 ISS cell surface
GO:0016020 NAS membrane
GO:0016337 NAS single organismal cell-cell adhesion
GO:0016787 IEA hydrolase activity
GO:0019233 IEA sensory perception of pain
GO:0030054 IEA cell junction
GO:0032230 ISS positive regulation of synaptic transmission, GABAergic
GO:0035418 ISS protein localization to synapse
GO:0035641 IEA locomotory exploration behavior
GO:0042043 ISS neurexin family protein binding
GO:0045202 ISS synapse
GO:0045211 NAS postsynaptic membrane
GO:0045217 NAS cell-cell junction maintenance
GO:0050804 ISS regulation of synaptic transmission
GO:0050808 ISS synapse organization
GO:0050839 ISS cell adhesion molecule binding
GO:0050885 IEA neuromuscular process controlling balance
GO:0051965 ISS positive regulation of synapse assembly
GO:0051968 ISS positive regulation of synaptic transmission, glutamatergic
GO:0060077 ISS inhibitory synapse
GO:0072553 ISS terminal button organization
GO:0097104 ISS postsynaptic membrane assembly
GO:0097105 ISS presynaptic membrane assembly
GO:0097116 ISS gephyrin clustering
GO:0097119 ISS postsynaptic density protein 95 clustering
GO:0097151 ISS positive regulation of inhibitory postsynaptic membrane potential
GO:2000311 ISS regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
GO:2000463 ISS positive regulation of excitatory postsynaptic membrane potential

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077329 nlgn2a neuroligin 2a protein_coding Danio_rerio
ENSDARG00000079251 nlgn2b neuroligin 2b protein_coding Danio_rerio
ENSMUSG00000051790 Nlgn2 neuroligin 2 protein_coding Mus_musculus

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