C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: neuroligin 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000575301 NLGN2-002 ENSG00000169992 9606 + 17:7404874-7418684 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBreastENST00000575301
Transcript ID Bladder Breast
ENST00000575301 0.193±0.00 0.580±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002087 ISS regulation of respiratory gaseous exchange by neurological system process
GO:0004872 IBA receptor activity
GO:0005887 ISS integral component of plasma membrane
GO:0007158 ISS neuron cell-cell adhesion
GO:0007416 ISS synapse assembly
GO:0008152 IEA metabolic process
GO:0009986 ISS cell surface
GO:0016020 NAS membrane
GO:0016337 NAS single organismal cell-cell adhesion
GO:0016787 IEA hydrolase activity
GO:0030054 IEA cell junction
GO:0032230 ISS positive regulation of synaptic transmission, GABAergic
GO:0035418 ISS protein localization to synapse
GO:0042043 ISS neurexin family protein binding
GO:0045202 ISS synapse
GO:0045211 NAS postsynaptic membrane
GO:0045217 NAS cell-cell junction maintenance
GO:0050804 ISS regulation of synaptic transmission
GO:0050808 ISS synapse organization
GO:0050839 ISS cell adhesion molecule binding
GO:0051965 ISS positive regulation of synapse assembly
GO:0051968 ISS positive regulation of synaptic transmission, glutamatergic
GO:0060077 ISS inhibitory synapse
GO:0072553 ISS terminal button organization
GO:0097104 ISS postsynaptic membrane assembly
GO:0097105 ISS presynaptic membrane assembly
GO:0097116 ISS gephyrin clustering
GO:0097119 ISS postsynaptic density protein 95 clustering
GO:0097151 ISS positive regulation of inhibitory postsynaptic membrane potential
GO:2000311 ISS regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
GO:2000463 ISS positive regulation of excitatory postsynaptic membrane potential

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000108634 Nlgn2-001 protein_coding Mus_musculus 0 4872
ENSMUST00000056484 Nlgn2-002 protein_coding Mus_musculus 0 3949
ENSMUST00000139893 Nlgn2-003 protein_coding Mus_musculus 0 682
ENSMUST00000140477 Nlgn2-004 retained_intron Mus_musculus 0 414

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