C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: neuroligin 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000051790 Nlgn2 10090 - 11:69823122-69837784 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000056484 Nlgn2-002 69823122-69834849 protein_coding
  ENSMUST00000108634 Nlgn2-001 69823122-69837784 protein_coding
  ENSMUST00000139893 Nlgn2-003 69827739-69834259 protein_coding
  ENSMUST00000140477 Nlgn2-004 69828044-69828559 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000056484ENSMUST00000108634
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000056484 5.111±1.25 5.595±1.60 6.800±0.27 29.397±13.32 5.617±2.74 4.222±0.58 1.382±0.48 1.260±0.65 1.034±0.51 6.031±0.60 0.708±0.40 17.436±6.07 1.612±0.41 0.714±0.09
ENSMUST00000108634 7.916±3.05 7.150±1.56 3.095±0.28 20.177±2.89 3.470±1.82 1.946±0.62 0.330±0.17 1.116±0.00 0.341±0.19 5.448±0.69 0.676±0.23 7.093±1.03 0.979±0.51 0.561±0.09

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00032K CIL_00032K_0002 CGP 11:69823122-69839618

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001966 ISS thigmotaxis
GO:0002087 IGI regulation of respiratory gaseous exchange by neurological system process
GO:0004872 IBA receptor activity
GO:0005515 IPI protein binding
GO:0005887 ISS integral component of plasma membrane
GO:0007158 ISS neuron cell-cell adhesion
GO:0007416 ISS synapse assembly
GO:0007630 ISS jump response
GO:0009986 ISS cell surface
GO:0019233 IMP sensory perception of pain
GO:0030054 IEA cell junction
GO:0032230 IMP positive regulation of synaptic transmission, GABAergic
GO:0035176 ISS social behavior
GO:0035418 IDA protein localization to synapse
GO:0035641 IMP locomotory exploration behavior
GO:0042043 IBA neurexin family protein binding
GO:0045202 IDA synapse
GO:0045211 IEA postsynaptic membrane
GO:0050804 IGI regulation of synaptic transmission
GO:0050808 ISS synapse organization
GO:0050839 IPI cell adhesion molecule binding
GO:0050885 IMP neuromuscular process controlling balance
GO:0051965 ISS positive regulation of synapse assembly
GO:0051968 IMP positive regulation of synaptic transmission, glutamatergic
GO:0060076 IC excitatory synapse
GO:0060077 IC inhibitory synapse
GO:0072553 ISS terminal button organization
GO:0097104 IDA postsynaptic membrane assembly
GO:0097105 IDA presynaptic membrane assembly
GO:0097116 IDA gephyrin clustering
GO:0097119 IDA postsynaptic density protein 95 clustering
GO:0097151 IMP positive regulation of inhibitory postsynaptic membrane potential
GO:2000311 IMP regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
GO:2000463 IMP positive regulation of excitatory postsynaptic membrane potential

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077329 nlgn2a neuroligin 2a protein_coding Danio_rerio
ENSDARG00000079251 nlgn2b neuroligin 2b protein_coding Danio_rerio
ENSG00000169992 NLGN2 neuroligin 2 protein_coding Homo_sapiens

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