C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000170381 SEMA3E 9606 - 7:83363906-83649010 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000307792 SEMA3E-001 83363906-83649010 protein_coding
  ENST00000427262 SEMA3E-002 83367485-83641431 protein_coding
  ENST00000442159 SEMA3E-004 83408368-83612648 protein_coding
  ENST00000453333 SEMA3E-003 83490188-83648810 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartLiverLungMuscleOvaryPlacentaTestisENST00000307792ENST00000427262ENST00000442159
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Liver Lung Muscle Ovary Placenta Testis
ENST00000307792 0.569±0.00 0.172±0.00 N/A 1.213±0.00 0.441±0.00 N/A 0.058±0.00 0.826±0.00 0.676±0.00 N/A 0.025±0.01 0.074±0.03 0.151±0.00
ENST00000427262 0.565±0.00 0.142±0.00 0.093±0.00 2.064±0.00 1.281±0.00 0.605±0.23 N/A 2.354±2.30 0.541±0.00 0.044±0.02 0.090±0.03 0.404±0.36 0.346±0.00
ENST00000442159 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.083±0.00 N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001569 ISS patterning of blood vessels
GO:0001953 ISS negative regulation of cell-matrix adhesion
GO:0002040 ISS sprouting angiogenesis
GO:0004872 IEA receptor activity
GO:0005515 IPI:IEA protein binding
GO:0005576 TAS extracellular region
GO:0005615 TAS extracellular space
GO:0007275 IEA multicellular organismal development
GO:0007411 TAS axon guidance
GO:0008360 ISS regulation of cell shape
GO:0016020 IEA membrane
GO:0016525 ISS negative regulation of angiogenesis
GO:0030215 IEA semaphorin receptor binding
GO:0050808 ISS synapse organization
GO:0071526 ISS semaphorin-plexin signaling pathway
GO:2000249 ISS regulation of actin cytoskeleton reorganization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000036571 sema3e sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E protein_coding Danio_rerio
ENSMUSG00000063531 Sema3e sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E protein_coding Mus_musculus

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