C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000063531 Sema3e 10090 + 5:14025276-14256689 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000073957 Sema3e-001 14025317-14256689 protein_coding
  ENSMUST00000130116 Sema3e-002 14025276-14254314 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000073957ENSMUST00000130116
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000073957 0.174±0.14 0.082±0.01 0.371±0.02 1.365±1.05 0.174±0.06 0.448±0.21 0.035±0.02 0.492±0.23 0.017±0.01 9.304±0.71 0.050±0.02 0.558±0.34 2.147±0.94 0.058±0.03
ENSMUST00000130116 0.505±0.45 0.084±0.03 0.089±0.01 1.308±1.23 0.171±0.07 0.484±0.14 0.104±0.04 0.287±0.12 0.016±0.01 10.376±0.93 0.016±0.00 0.582±0.27 8.488±7.04 0.225±0.09

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003CW CIL_0003CW_0002 CGP 5:14025276-14860184

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001569 IMP patterning of blood vessels
GO:0001953 IMP negative regulation of cell-matrix adhesion
GO:0002040 IMP sprouting angiogenesis
GO:0004872 IEA receptor activity
GO:0005515 IPI protein binding
GO:0005576 NAS extracellular region
GO:0007399 IEA nervous system development
GO:0008360 IMP regulation of cell shape
GO:0016020 IEA membrane
GO:0016525 IMP negative regulation of angiogenesis
GO:0030154 IEA cell differentiation
GO:0030215 IPI semaphorin receptor binding
GO:0050808 IMP synapse organization
GO:0071526 IMP semaphorin-plexin signaling pathway
GO:2000249 IMP regulation of actin cytoskeleton reorganization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000036571 sema3e sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E protein_coding Danio_rerio
ENSG00000170381 SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E protein_coding Homo_sapiens

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