C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: keratin 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000170477 KRT4 9606 - 12:52806549-52814551 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000548097 KRT4-002 52806600-52814116 nonsense_mediated_decay
  ENST00000549295 KRT4-004 52809075-52810927 retained_intron
  ENST00000551436 KRT4-005 52811446-52813616 retained_intron
  ENST00000551956 KRT4-001 52806549-52814551 protein_coding
  ENST00000552668 KRT4-003 52809383-52814116 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBreastColonHeartKidneyLungOvaryPlacentaTestisENST00000548097ENST00000551436ENST00000551956
Transcript ID Adipose Adrenal Breast Colon Heart Kidney Lung Ovary Placenta Testis
ENST00000548097 0.860±0.00 N/A N/A 0.021±0.00 N/A N/A 1.564±0.00 41.073±47.59 0.067±0.02 0.019±0.00
ENST00000551436 N/A N/A N/A N/A N/A N/A N/A N/A 0.205±0.00 N/A
ENST00000551956 N/A 0.008±0.00 0.051±0.00 N/A 0.021±0.00 0.339±0.00 0.609±0.41 70.967±90.42 0.096±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00033Q CIL_00033Q_000L CGP 12:52789685-52814551
CIL_00033Q CIL_00033Q_000C CGP 12:52806549-52834295

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005198 IEA structural molecule activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005882 NAS:IEA intermediate filament
GO:0007010 IMP cytoskeleton organization
GO:0009986 IDA cell surface
GO:0030855 ISS epithelial cell differentiation
GO:0045095 IDA keratin filament
GO:0045111 IDA intermediate filament cytoskeleton
GO:0050680 ISS negative regulation of epithelial cell proliferation

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000017624 krt4 keratin 4 protein_coding Danio_rerio
ENSDARG00000043242 si:dkey-222f2.1 si:dkey-222f2.1 protein_coding Danio_rerio
ENSDARG00000058358 krt8 keratin 8 protein_coding Danio_rerio
ENSDARG00000058371 krt5 keratin 5 protein_coding Danio_rerio
ENSDARG00000058462 zgc:158846 zgc:158846 protein_coding Danio_rerio
ENSMUSG00000059668 Krt4 keratin 4 protein_coding Mus_musculus

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