C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: HtrA serine peptidase 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000170801 HTRA3 9606 + 4:8269765-8307111 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000307358 HTRA3-001 8269765-8307111 protein_coding
  ENST00000382512 HTRA3-002 8269777-8296474 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000307358ENST00000382512
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000307358 30.187±0.00 3.099±0.00 0.030±0.00 0.359±0.00 17.917±13.07 12.889±12.50 10.908±8.56 3.516±0.00 1.423±0.52 20.606±18.77 4.139±2.20 51.218±56.45 26.931±7.35 6.347±1.88
ENST00000382512 12.430±0.00 0.574±0.00 0.080±0.00 0.169±0.05 3.871±0.00 1.927±1.70 4.785±0.00 0.483±0.44 0.749±0.60 6.676±0.00 2.979±0.00 10.243±0.00 6.592±2.26 1.733±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001558 IEA regulation of cell growth
GO:0003824 IEA catalytic activity
GO:0004175 IDA endopeptidase activity
GO:0004252 IEA serine-type endopeptidase activity
GO:0005515 IPI:IEA protein binding
GO:0005520 IEA insulin-like growth factor binding
GO:0005576 IEA extracellular region
GO:0006508 IDA:IEA proteolysis
GO:0008236 IDA serine-type peptidase activity
GO:0030512 ISS negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030514 ISS negative regulation of BMP signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010925 HTRA3 (1 of 3) HtrA serine peptidase 3 protein_coding Danio_rerio
ENSMUSG00000029096 Htra3 HtrA serine peptidase 3 protein_coding Mus_musculus

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