C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: HtrA serine peptidase 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000029096 Htra3 10090 - 5:35652041-35679782 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000087629 Htra3-001 35652041-35679782 protein_coding
  ENSMUST00000114233 Htra3-002 35661559-35679472 protein_coding
  ENSMUST00000129459 Htra3-004 35668193-35671552 processed_transcript
  ENSMUST00000137935 Htra3-003 35668230-35671553 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000087629ENSMUST00000114233ENSMUST00000129459
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000087629 122.235±31.30 26.703±6.97 47.005±0.69 3.446±0.76 116.011±18.17 24.533±4.15 35.870±5.15 3.476±0.73 0.418±0.16 17.146±2.38 4.583±1.23 63.406±19.95 17.199±12.33 4.089±2.08
ENSMUST00000114233 48.162±0.68 34.015±18.31 N/A 0.645±0.00 59.018±3.12 6.517±1.11 8.232±0.00 0.774±0.10 0.133±0.04 5.370±1.51 2.606±0.50 41.241±24.15 N/A 1.263±0.06
ENSMUST00000129459 N/A N/A N/A N/A N/A N/A N/A N/A 0.545±0.13 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00032E CIL_00032E_0002 CGP 5:35583040-35679782
CIL_00032F CIL_00032F_0002 CGP 5:35652041-35729276

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001558 IEA regulation of cell growth
GO:0004175 IEA endopeptidase activity
GO:0004252 IEA serine-type endopeptidase activity
GO:0005515 IPI protein binding
GO:0005520 IEA insulin-like growth factor binding
GO:0005576 IEA extracellular region
GO:0006508 IDA proteolysis
GO:0008236 IDA serine-type peptidase activity
GO:0030512 IDA negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030514 IDA negative regulation of BMP signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010925 HTRA3 (1 of 3) HtrA serine peptidase 3 protein_coding Danio_rerio
ENSG00000170801 HTRA3 HtrA serine peptidase 3 protein_coding Homo_sapiens

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