C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein kinase (cAMP-dependent, catalytic) inhibitor alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000171033 PKIA 9606 + 8:78516139-78605267 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000352966 PKIA-002 78516355-78603185 protein_coding
  ENST00000396418 PKIA-001 78516139-78605267 protein_coding
  ENST00000518467 PKIA-003 78591231-78602098 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000352966ENST00000396418ENST00000518467
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000352966 N/A 0.359±0.00 0.201±0.00 13.821±0.00 0.605±0.00 0.807±0.18 14.542±1.86 1.526±0.00 1.424±1.38 1.799±0.00 61.967±0.00 0.530±0.38 0.438±0.13 0.345±0.00
ENST00000396418 N/A 0.404±0.00 0.384±0.00 9.380±0.92 0.551±0.02 0.224±0.04 9.848±3.92 0.554±0.00 0.016±0.00 1.084±0.06 32.910±0.00 0.384±0.29 0.302±0.04 0.216±0.08
ENST00000518467 0.111±0.00 N/A N/A N/A N/A N/A N/A N/A 0.063±0.00 1.528±0.00 N/A 2.343±0.00 N/A 1.744±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002P2 CIL_0002P2_0001 CGP 8:78516139-78719765

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0004862 TAS:IEA cAMP-dependent protein kinase inhibitor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0006469 IEA negative regulation of protein kinase activity
GO:0010389 IEA regulation of G2/M transition of mitotic cell cycle
GO:0034236 IPI protein kinase A catalytic subunit binding
GO:0042308 IEA negative regulation of protein import into nucleus
GO:0043086 IEA negative regulation of catalytic activity
GO:2000480 IDA negative regulation of cAMP-dependent protein kinase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000027499 Pkia protein kinase inhibitor, alpha protein_coding Mus_musculus

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