C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein kinase inhibitor, alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000027499 Pkia 10090 + 3:7366604-7445366 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000028999 Pkia-201 7366604-7445366 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000028999
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000028999 3.246±1.32 0.915±0.49 4.356±0.14 44.346±21.28 2.715±1.20 2.133±0.29 14.414±3.50 5.441±1.04 0.321±0.17 4.922±0.57 48.381±52.83 4.872±2.27 0.555±0.50 0.328±0.15

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002P2 CIL_0002P2_0002 CGP 3:7366604-7553848

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0004862 ISO cAMP-dependent protein kinase inhibitor activity
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006469 IDA negative regulation of protein kinase activity
GO:0010389 IMP regulation of G2/M transition of mitotic cell cycle
GO:0034236 IEA protein kinase A catalytic subunit binding
GO:0042308 IDA negative regulation of protein import into nucleus
GO:0043086 IDA negative regulation of catalytic activity
GO:2000480 ISO negative regulation of cAMP-dependent protein kinase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000171033 PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha protein_coding Homo_sapiens

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