C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: complement component 3a receptor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000171860 C3AR1 9606 - 12:8058302-8066471 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000307637 C3AR1-001 8058302-8066471 protein_coding
  ENST00000546241 C3AR1-002 8059746-8066337 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000307637ENST00000546241
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000307637 6.242±0.00 4.193±0.00 0.159±0.00 1.465±0.69 3.306±0.78 1.371±0.00 1.735±1.34 2.550±2.19 2.085±0.13 4.567±3.21 0.621±0.00 2.257±1.10 16.447±7.16 1.587±1.08
ENST00000546241 N/A N/A N/A N/A N/A N/A 0.406±0.00 N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00001E CIL_00001E_0001 CGP 12:8032703-8066471
CIL_00001J CIL_00001J_0001 CGP 12:8058302-8097771

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002430 TAS complement receptor mediated signaling pathway
GO:0004435 TAS phosphatidylinositol phospholipase C activity
GO:0004876 TAS complement component C3a receptor activity
GO:0004930 IGI:IEA G-protein coupled receptor activity
GO:0004943 IEA C3a anaphylatoxin receptor activity
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006935 IEA chemotaxis
GO:0006954 TAS inflammatory response
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007204 IGI positive regulation of cytosolic calcium ion concentration
GO:0008015 TAS blood circulation
GO:0008152 TAS metabolic process
GO:0010575 IEA positive regulation vascular endothelial growth factor production
GO:0010759 IEA positive regulation of macrophage chemotaxis
GO:0016021 IEA integral component of membrane
GO:0045766 IEA positive regulation of angiogenesis
GO:0090023 IEA positive regulation of neutrophil chemotaxis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000031749 C3AR1 C3a anaphylatoxin chemotactic receptor protein_coding Danio_rerio
ENSMUSG00000040552 C3ar1 complement component 3a receptor 1 protein_coding Mus_musculus

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