C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: chemokine (C-X-C motif) receptor 6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000172215 CXCR6 9606 + 3:45940933-45948353 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000304552 CXCR6-001 45943472-45948353 protein_coding
  ENST00000438735 CXCR6-002 45940933-45948337 protein_coding
  ENST00000457814 CXCR6-003 45945049-45947510 protein_coding
  ENST00000458629 CXCR6-004 45945019-45947823 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000304552ENST00000438735ENST00000457814ENST00000458629
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000304552 N/A 2.337±0.00 N/A N/A 0.857±0.68 0.225±0.00 0.154±0.06 0.444±0.11 0.724±0.05 1.933±0.00 0.792±0.00 0.780±0.17 1.960±0.46 0.076±0.03
ENST00000438735 0.037±0.00 N/A N/A 0.142±0.11 0.638±0.00 N/A N/A N/A N/A N/A 0.653±0.63 0.262±0.02 3.450±1.12 N/A
ENST00000457814 0.147±0.00 N/A 0.850±0.00 N/A N/A 0.076±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000458629 0.034±0.00 N/A 0.377±0.00 0.088±0.07 0.338±0.30 0.279±0.25 0.261±0.12 0.236±0.00 0.861±0.00 0.561±0.33 0.184±0.14 0.425±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003OM CIL_0003OM_0001 CGP 3:45917899-45995824
CIL_0003OL CIL_0003OL_0001 CGP 3:45940933-46027742

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004930 TAS:IEA G-protein coupled receptor activity
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006935 IEA chemotaxis
GO:0006954 IEA inflammatory response
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0015026 IEA coreceptor activity
GO:0016021 IEA integral component of membrane
GO:0016494 IEA C-X-C chemokine receptor activity
GO:0019079 TAS viral genome replication
GO:0070098 IEA chemokine-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000048521 Cxcr6 chemokine (C-X-C motif) receptor 6 protein_coding Mus_musculus

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