C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ATP-binding cassette, sub-family G (WHITE), member 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000172350 ABCG4 9606 + 11:119149012-119162653 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000524604 ABCG4-005 119149253-119154359 protein_coding
  ENST00000533694 ABCG4-004 119152875-119160371 retained_intron
  ENST00000534402 ABCG4-006 119155630-119158495 retained_intron
  ENST00000615496 ABCG4-002 119149513-119161436 protein_coding
  ENST00000619701 ABCG4-001 119149012-119162653 protein_coding
  ENST00000622721 ABCG4-003 119149896-119161648 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartLiverMuscleOvaryPlacentaTestisENST00000524604ENST00000533694ENST00000534402ENST00000615496ENST00000619701ENST00000622721
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Liver Muscle Ovary Placenta Testis
ENST00000524604 0.210±0.00 0.271±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000533694 0.013±0.00 N/A 0.024±0.00 N/A N/A N/A N/A N/A N/A 0.031±0.01 0.022±0.00 N/A
ENST00000534402 N/A N/A N/A N/A N/A N/A N/A N/A 0.066±0.00 N/A N/A N/A
ENST00000615496 N/A N/A N/A N/A 0.108±0.00 0.025±0.00 N/A N/A N/A 0.179±0.00 0.064±0.00 1.034±0.00
ENST00000619701 N/A 0.098±0.00 N/A 1.004±0.22 N/A 0.066±0.00 0.256±0.00 0.029±0.00 N/A 0.140±0.00 0.048±0.00 2.573±0.00
ENST00000622721 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.077±0.00 0.053±0.02 N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005886 TAS plasma membrane
GO:0006200 IEA ATP catabolic process
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016887 IEA ATPase activity
GO:0017127 TAS cholesterol transporter activity
GO:0033344 TAS cholesterol efflux
GO:0042803 IDA protein homodimerization activity
GO:0046982 IPI protein heterodimerization activity
GO:0055085 TAS transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061047 abcg4a ATP-binding cassette, sub-family G (WHITE), member 4a protein_coding Danio_rerio
ENSDARG00000078068 abcg4b ATP-binding cassette, sub-family G (WHITE), member 4b protein_coding Danio_rerio
ENSMUSG00000032131 Abcg4 ATP-binding cassette, sub-family G (WHITE), member 4 protein_coding Mus_musculus

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