C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: alanine-glyoxylate aminotransferase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000172482 AGXT 9606 + 2:240868479-240880502 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000307503 AGXT-001 240868479-240879120 protein_coding
  ENST00000470255 AGXT-002 240876913-240880502 retained_intron
  ENST00000472436 AGXT-003 240868846-240873468 retained_intron
  ENST00000476698 AGXT-004 240871189-240876013 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000307503ENST00000470255ENST00000472436ENST00000476698
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000307503 0.131±0.00 N/A 2.270±0.00 0.056±0.00 0.371±0.03 N/A N/A 38.344±37.90 414.150±414.11 N/A 0.490±0.00 N/A 1.401±0.81 N/A
ENST00000470255 0.017±0.00 0.195±0.00 N/A 0.230±0.00 0.234±0.00 0.103±0.00 0.052±0.00 0.116±0.00 N/A 0.085±0.00 0.014±0.00 0.054±0.03 N/A 0.126±0.02
ENST00000472436 N/A N/A N/A 0.147±0.00 0.177±0.00 N/A N/A N/A N/A N/A N/A 0.072±0.00 N/A N/A
ENST00000476698 0.078±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.189±0.00 0.269±0.00 0.755±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00046R CIL_00046R_0001 CGP 2:240713764-240880502
CIL_0003LC CIL_0003LC_0001 CGP 2:240868479-240896889

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004760 IEA serine-pyruvate transaminase activity
GO:0005102 IPI receptor binding
GO:0005515 IPI protein binding
GO:0005739 IEA mitochondrion
GO:0005759 IEA mitochondrial matrix
GO:0005777 IDA peroxisome
GO:0005782 IDA peroxisomal matrix
GO:0008152 IEA metabolic process
GO:0008453 IDA alanine-glyoxylate transaminase activity
GO:0008483 IDA transaminase activity
GO:0009436 IDA glyoxylate catabolic process
GO:0016597 IDA amino acid binding
GO:0019265 IDA glycine biosynthetic process, by transamination of glyoxylate
GO:0019448 IDA L-cysteine catabolic process
GO:0030170 IMP pyridoxal phosphate binding
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0042803 IDA protein homodimerization activity
GO:0042853 IDA L-alanine catabolic process
GO:0042866 IEA pyruvate biosynthetic process
GO:0044281 TAS small molecule metabolic process
GO:0046487 IMP glyoxylate metabolic process
GO:0046724 IEA oxalic acid secretion
GO:0051384 IEA response to glucocorticoid
GO:0051591 IEA response to cAMP

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018478 agxtb alanine-glyoxylate aminotransferase b protein_coding Danio_rerio
ENSDARG00000052099 agxta alanine-glyoxylate aminotransferase a protein_coding Danio_rerio
ENSMUSG00000026272 Agxt alanine-glyoxylate aminotransferase protein_coding Mus_musculus

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