C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: EGF-like-domain, multiple 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000172889 EGFL7 9606 + 9:136658856-136672678 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000308874 EGFL7-201 136662927-136672677 protein_coding
  ENST00000371698 EGFL7-003 136665792-136672678 protein_coding
  ENST00000371699 EGFL7-001 136658856-136672678 protein_coding
  ENST00000406555 EGFL7-002 136662930-136672678 protein_coding
  ENST00000490469 EGFL7-004 136662933-136669674 processed_transcript
  ENST00000492002 EGFL7-006 136665788-136671993 processed_transcript
  ENST00000492862 EGFL7-005 136662932-136668673 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000308874ENST00000371698ENST00000406555ENST00000490469
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000308874 N/A N/A N/A N/A 0.324±0.00 N/A 1.132±0.00 0.510±0.00 N/A N/A N/A N/A N/A
ENST00000371698 8.332±0.00 N/A 10.928±0.00 N/A 0.532±0.00 3.111±0.00 10.835±0.00 6.628±0.00 N/A 2.738±0.00 10.409±8.25 60.595±26.45 14.490±9.71
ENST00000406555 18.644±0.00 29.576±0.00 2.194±0.00 20.224±0.00 18.128±0.00 7.768±0.00 8.881±0.00 5.140±0.00 54.528±0.00 3.494±0.00 16.001±3.48 56.597±40.89 10.155±0.00
ENST00000490469 N/A N/A N/A 1.178±0.00 2.879±0.00 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003X5 CIL_0003X5_0001 CGP 9:136494444-136672678
CIL_0004U6 CIL_0004U6_0002 CGP 9:136658856-136687423

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0001568 ISS blood vessel development
GO:0001570 ISS vasculogenesis
GO:0001938 IMP positive regulation of endothelial cell proliferation
GO:0005112 IEA Notch binding
GO:0005509 IEA calcium ion binding
GO:0005515 IEA protein binding
GO:0005576 ISS extracellular region
GO:0005615 IEA extracellular space
GO:0007155 IEA cell adhesion
GO:0030336 IEA negative regulation of cell migration
GO:0031012 IDA extracellular matrix
GO:0045746 IMP negative regulation of Notch signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000043376 egfl7 EGF-like-domain, multiple 7 protein_coding Danio_rerio
ENSMUSG00000026921 Egfl7 EGF-like domain 7 protein_coding Mus_musculus

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