C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: EGF-like domain 7
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000026921 Egfl7 10090 + 2:26580014-26593120 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000100290 Egfl7-002 26583864-26592681 protein_coding
  ENSMUST00000102907 Egfl7-003 26583880-26592682 protein_coding
  ENSMUST00000131112 Egfl7-007 26590965-26592676 protein_coding
  ENSMUST00000139801 Egfl7-011 26583905-26593120 nonsense_mediated_decay
  ENSMUST00000145575 Egfl7-006 26586672-26590939 protein_coding
  ENSMUST00000147351 Egfl7-008 26589335-26591563 retained_intron
  ENSMUST00000149460 Egfl7-012 26586661-26590908 processed_transcript
  ENSMUST00000149789 Egfl7-010 26591435-26592682 protein_coding
  ENSMUST00000150404 Egfl7-014 26588543-26592443 protein_coding
  ENSMUST00000152713 Egfl7-004 26580014-26589384 protein_coding
  ENSMUST00000152988 Egfl7-009 26591434-26592682 protein_coding
  ENSMUST00000166920 Egfl7-001 26581056-26592684 protein_coding
  ENSMUST00000172683 Egfl7-019 26592147-26592682 retained_intron
  ENSMUST00000173777 Egfl7-018 26591446-26592290 retained_intron
  ENSMUST00000173920 Egfl7-013 26586689-26590489 protein_coding
  ENSMUST00000174211 Egfl7-005 26586630-26592681 protein_coding
  ENSMUST00000174465 Egfl7-017 26592023-26592681 processed_transcript
  ENSMUST00000174572 Egfl7-015 26590520-26590972 retained_intron
  ENSMUST00000174656 Egfl7-016 26591029-26592682 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000100290ENSMUST00000102907ENSMUST00000145575ENSMUST00000147351ENSMUST00000150404ENSMUST00000152988ENSMUST00000172683ENSMUST00000173777ENSMUST00000174211
Transcript ID Bladder Brain Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000100290 N/A 16.934±0.00 N/A N/A N/A N/A N/A N/A N/A 17.917±6.19
ENSMUST00000102907 27.032±1.82 28.466±2.22 33.273±0.00 74.731±13.55 61.498±2.80 22.956±6.43 384.605±117.56 19.498±3.92 85.472±14.63 19.036±1.53
ENSMUST00000145575 N/A N/A N/A N/A N/A N/A 383.483±0.00 N/A N/A N/A
ENSMUST00000147351 N/A 16.053±0.00 N/A N/A N/A N/A N/A N/A 21.264±0.00 18.989±3.15
ENSMUST00000150404 N/A N/A N/A N/A N/A N/A N/A N/A 20.444±0.00 22.349±0.00
ENSMUST00000152988 35.019±0.00 N/A N/A N/A N/A N/A 423.097±105.31 15.294±0.00 N/A N/A
ENSMUST00000172683 N/A N/A N/A N/A N/A N/A N/A 23.645±1.59 43.856±0.00 N/A
ENSMUST00000173777 33.251±4.28 N/A N/A 51.383±0.00 N/A N/A N/A 18.719±3.89 20.349±7.17 N/A
ENSMUST00000174211 N/A N/A N/A N/A N/A 27.641±3.72 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003X5 CIL_0003X5_0002 CGP 2:26457903-26593120

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0001568 IEP blood vessel development
GO:0001570 IEP vasculogenesis
GO:0001938 IEA positive regulation of endothelial cell proliferation
GO:0005112 IPI Notch binding
GO:0005509 NAS calcium ion binding
GO:0005576 IDA extracellular region
GO:0005615 IDA extracellular space
GO:0007155 IEA cell adhesion
GO:0030334 TAS regulation of cell migration
GO:0030336 IDA negative regulation of cell migration
GO:0031012 IEA extracellular matrix
GO:0045746 IEA negative regulation of Notch signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000043376 egfl7 EGF-like-domain, multiple 7 protein_coding Danio_rerio
ENSG00000172889 EGFL7 EGF-like-domain, multiple 7 protein_coding Homo_sapiens

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