C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: Dab, reelin signal transducer, homolog 1 (Drosophila)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000173406 DAB1 9606 - 1:56994778-58546734 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000332102 DAB1-008 57062890-57291065 protein_coding
  ENST00000371230 DAB1-005 57070734-57424057 protein_coding
  ENST00000371231 DAB1-010 57010695-57291065 protein_coding
  ENST00000371232 DAB1-007 57015352-57291065 protein_coding
  ENST00000371236 DAB1-004 56994778-57424057 protein_coding
  ENST00000414851 DAB1-201 56994782-57291168 protein_coding
  ENST00000420954 DAB1-202 56998025-57291066 protein_coding
  ENST00000473821 DAB1-006 57145417-57307364 processed_transcript
  ENST00000477280 DAB1-002 57826071-57884085 processed_transcript
  ENST00000485760 DAB1-001 56997899-58546734 processed_transcript
  ENST00000489267 DAB1-009 57071178-57136583 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainColonHeartOvaryENST00000371236ENST00000414851
Transcript ID Adipose Brain Colon Heart Ovary
ENST00000371236 N/A N/A N/A N/A 0.393±0.00
ENST00000414851 0.208±0.00 1.806±0.02 0.319±0.00 0.509±0.12 0.413±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00005G CIL_00005G_0002 CGP 1:56929210-58546734
CIL_00005F CIL_00005F_0002 CGP 1:56994778-58546802

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001764 IEA neuron migration
GO:0005515 IEA protein binding
GO:0005829 IEA cytosol
GO:0005903 IEA brush border
GO:0007162 IEA negative regulation of cell adhesion
GO:0007264 IEA small GTPase mediated signal transduction
GO:0007420 IEA brain development
GO:0007494 IEA midgut development
GO:0007628 IEA adult walking behavior
GO:0014069 IEA postsynaptic density
GO:0016020 IEA membrane
GO:0016358 IEA dendrite development
GO:0021517 IEA ventral spinal cord development
GO:0021589 IEA cerebellum structural organization
GO:0021795 IEA cerebral cortex cell migration
GO:0021799 IEA cerebral cortex radially oriented cell migration
GO:0021813 IEA cell-cell adhesion involved in neuronal-glial interactions involved in cerebral cortex radial glia guided migration
GO:0021942 IEA radial glia guided migration of Purkinje cell
GO:0021987 IEA cerebral cortex development
GO:0042493 IEA response to drug
GO:0043005 IEA neuron projection
GO:0043025 IEA neuronal cell body
GO:0043548 IEA phosphatidylinositol 3-kinase binding
GO:0045177 IEA apical part of cell
GO:0045666 IEA positive regulation of neuron differentiation
GO:0045860 IEA positive regulation of protein kinase activity
GO:0046426 IEA negative regulation of JAK-STAT cascade
GO:0048471 IEA perinuclear region of cytoplasm
GO:0048712 IEA negative regulation of astrocyte differentiation
GO:0050771 IEA negative regulation of axonogenesis
GO:0051645 IEA Golgi localization
GO:0097477 IEA lateral motor column neuron migration

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003290 dab1b disabled homolog 1b (Drosophila) protein_coding Danio_rerio
ENSDARG00000059939 dab1a disabled homolog 1a (Drosophila) protein_coding Danio_rerio
ENSMUSG00000028519 Dab1 disabled 1 protein_coding Mus_musculus

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