C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: huntingtin-associated protein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000173805 HAP1 9606 - 17:41717742-41734644 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000310778 HAP1-006 41722640-41734644 protein_coding
  ENST00000341193 HAP1-002 41722640-41734644 protein_coding
  ENST00000347901 HAP1-001 41722640-41734644 protein_coding
  ENST00000393939 HAP1-007 41720813-41734644 protein_coding
  ENST00000442364 HAP1-003 41717742-41725141 protein_coding
  ENST00000455021 HAP1-005 41717742-41725897 protein_coding
  ENST00000458656 HAP1-004 41717742-41725081 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000310778ENST00000341193ENST00000347901ENST00000393939ENST00000458656
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000310778 N/A N/A N/A 0.949±0.00 N/A N/A N/A N/A N/A N/A N/A 2.828±0.00 0.059±0.00 0.132±0.00
ENST00000341193 N/A N/A 0.045±0.00 1.365±0.78 0.071±0.03 0.159±0.03 N/A N/A N/A 0.134±0.00 N/A 0.934±0.06 0.173±0.11 0.300±0.00
ENST00000347901 N/A N/A N/A N/A N/A N/A N/A 0.268±0.00 N/A N/A N/A 0.767±0.25 N/A 1.158±0.00
ENST00000393939 0.051±0.00 0.079±0.00 N/A N/A 0.178±0.00 0.032±0.00 0.045±0.00 N/A 0.020±0.00 0.081±0.08 0.011±0.01 N/A 0.029±0.00 0.164±0.02
ENST00000458656 N/A N/A N/A N/A N/A 0.322±0.00 N/A 0.312±0.00 N/A 0.031±0.00 N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007BD CIL_0007BD_0001 CGP 17:41712326-41734644
CIL_0000TS CIL_0000TS_0002 CGP 17:41717742-41786931

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005739 IEA mitochondrion
GO:0005764 IEA lysosome
GO:0005776 IEA autophagic vacuole
GO:0005783 IEA endoplasmic reticulum
GO:0005856 TAS cytoskeleton
GO:0006887 IEA exocytosis
GO:0006914 IEA autophagy
GO:0007268 TAS synaptic transmission
GO:0007420 NAS brain development
GO:0008089 ISS anterograde axon cargo transport
GO:0008090 ISS retrograde axon cargo transport
GO:0008104 IMP protein localization
GO:0015031 IEA protein transport
GO:0015629 TAS actin cytoskeleton
GO:0016023 IEA cytoplasmic membrane-bounded vesicle
GO:0016234 IDA inclusion body
GO:0017157 ISS regulation of exocytosis
GO:0021549 IEA cerebellum development
GO:0021979 IEA hypothalamus cell differentiation
GO:0030030 IEA cell projection organization
GO:0030054 IEA cell junction
GO:0031587 ISS positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
GO:0032230 ISS positive regulation of synaptic transmission, GABAergic
GO:0032901 ISS positive regulation of neurotrophin production
GO:0042995 IEA cell projection
GO:0044325 ISS ion channel binding
GO:0045202 IEA synapse
GO:0045742 ISS positive regulation of epidermal growth factor receptor signaling pathway
GO:0047496 IEA vesicle transport along microtubule
GO:0048011 ISS neurotrophin TRK receptor signaling pathway
GO:0048403 ISS brain-derived neurotrophic factor binding
GO:0050769 IEA positive regulation of neurogenesis
GO:1902430 ISS negative regulation of beta-amyloid formation
GO:1902513 ISS regulation of organelle transport along microtubule
GO:1902857 ISS positive regulation of nonmotile primary cilium assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074508 HAP1 huntingtin-associated protein 1 protein_coding Danio_rerio
ENSMUSG00000006930 Hap1 huntingtin-associated protein 1 protein_coding Mus_musculus

Loading