C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: polo-like kinase 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000173846 PLK3 9606 + 1:44800225-44805990 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000372201 PLK3-001 44800225-44805990 protein_coding
  ENST00000461358 PLK3-006 44803337-44804689 processed_transcript
  ENST00000461769 PLK3-005 44804218-44805121 processed_transcript
  ENST00000465443 PLK3-002 44800388-44805990 processed_transcript
  ENST00000476731 PLK3-007 44801634-44803621 processed_transcript
  ENST00000492398 PLK3-003 44803268-44805950 processed_transcript
  ENST00000493100 PLK3-004 44804621-44805600 processed_transcript

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000372201ENST00000461358ENST00000461769ENST00000465443ENST00000476731ENST00000492398ENST00000493100
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000372201 3.368±0.00 4.087±0.00 0.857±0.00 2.607±0.00 2.338±1.18 0.905±0.05 1.010±0.00 1.630±1.15 0.493±0.03 6.354±4.67 1.448±0.00 5.893±2.96 6.716±2.12 1.410±0.35
ENST00000461358 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.099±0.00 N/A N/A
ENST00000461769 N/A N/A N/A N/A N/A N/A 0.489±0.21 N/A N/A N/A 0.821±0.00 N/A N/A N/A
ENST00000465443 N/A 1.484±0.00 N/A 0.765±0.00 1.270±0.00 0.796±0.00 0.067±0.00 N/A 0.507±0.11 N/A N/A 3.890±0.00 2.015±0.00 0.631±0.00
ENST00000476731 2.900±0.00 N/A N/A 3.679±0.00 N/A N/A N/A N/A N/A 4.049±0.00 N/A 6.217±0.00 4.331±0.00 1.284±0.00
ENST00000492398 N/A 2.823±0.00 N/A N/A 1.774±0.00 N/A N/A N/A 0.350±0.00 7.538±0.00 N/A 4.997±0.08 4.733±1.18 1.932±0.00
ENST00000493100 N/A 3.869±0.00 N/A N/A 2.453±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00093U CIL_00093U_0001 VISTA 1:44224152-44825477

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 IMP G1/S transition of mitotic cell cycle
GO:0000086 TAS G2/M transition of mitotic cell cycle
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000302 IDA response to reactive oxygen species
GO:0002039 IDA p53 binding
GO:0004672 IEA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0005795 IDA Golgi stack
GO:0005813 IDA centrosome
GO:0006468 IEA protein phosphorylation
GO:0006915 TAS apoptotic process
GO:0006970 IDA response to osmotic stress
GO:0006974 IMP cellular response to DNA damage stimulus
GO:0007093 TAS mitotic cell cycle checkpoint
GO:0007113 TAS endomitotic cell cycle
GO:0009314 IDA response to radiation
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0030425 IEA dendrite
GO:0031122 IMP cytoplasmic microtubule organization
GO:0032465 IMP regulation of cytokinesis
GO:0043025 IEA neuronal cell body
GO:0043066 IDA negative regulation of apoptotic process
GO:0043491 ISS protein kinase B signaling
GO:0044819 ISS mitotic G1/S transition checkpoint
GO:0051302 IDA regulation of cell division
GO:0090166 IDA Golgi disassembly
GO:0090316 IMP positive regulation of intracellular protein transport
GO:2000777 IDA positive regulation of proteasomal ubiquitin-dependent protein catabolic process involved in cellular response to hypoxia

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000038754 plk3 polo-like kinase 3 (Drosophila) protein_coding Danio_rerio
ENSMUSG00000028680 Plk3 polo-like kinase 3 protein_coding Mus_musculus

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